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VPS35 anticorps

VPS35 Reactivité: Humain WB, IP, IF, ICC Hôte: Souris Monoclonal 7E4 unconjugated
N° du produit ABIN6932908
  • Antigène Voir toutes VPS35 Anticorps
    VPS35 (Vacuolar Protein Sorting 35 (VPS35))
    Reactivité
    • 89
    • 23
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 54
    • 34
    • 1
    Souris
    Clonalité
    • 62
    • 27
    Monoclonal
    Conjugué
    • 21
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    Cet anticorp VPS35 est non-conjugé
    Application
    • 67
    • 53
    • 44
    • 43
    • 37
    • 8
    • 4
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    Ubiquitous. Highly expressed in brain, colon, heart, kidney, ovary, placenta, skeletal muscle, small intestine, testis, thymus.,Detects ~92 kDa.
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    Protein G Purified
    Immunogène
    Full length recombinant human VSP35
    Clone
    7E4
    Isotype
    IgG2a
    Top Product
    Discover our top product VPS35 Anticorps primaire
  • Indications d'application
    • WB (1:1000)
    • ICC/IF (1:200)
    • IP (1:200)
    • optimal dilutions for assays should be determined by the user.
    Commentaires

    A 1:1000 dilution of ABIN6932908 was sufficient for detection of VPS35 in 10 μg of SH-SY5Y by ECL immunoblot analysis using Goat Anti-Mouse IgG:HRP as the secondary antibody.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.09 % Sodium azide, Storage buffer may change when conjugated
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    -20°C
  • Antigène
    VPS35 (Vacuolar Protein Sorting 35 (VPS35))
    Autre désignation
    VPS35 (VPS35 Produits)
    Sujet
    Vacuolar Protein Sorter-35 (VPS35) is a component of the retromer complex, which is essential for endosome-to-Golgi retrieval of membrane proteins. VPS35 mutations such as D620N have been linked to Parkinson's Disease (PD) (1,2) and affect retromer function, protein homeostasis, and mitochondria (3).
    ID gène
    55737
    NCBI Accession
    NP_060676
    UniProt
    Q96QK1
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