Glypican 3 anticorps (AA 511-580) (CF®555)
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- Antigène Voir toutes Glypican 3 (GPC3) Anticorps
- Glypican 3 (GPC3)
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Épitope
- AA 511-580
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Glypican 3 est conjugé à/à la CF®555
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Application
- Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (IHC), Staining Methods (StM)
- Purification
- Purified by Protein A/G
- Immunogène
- A recombinant fragment containing amino acids 511-580 of human glypican-3
- Clone
- SPM595
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product GPC3 Anticorps primaire
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- Indications d'application
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Positive Control: 293T cells. Hepatocellular carcinoma.
Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- Restrictions
- For Research Use only
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- Concentration
- 100 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Antibody with azide - store at 4 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Date de péremption
- 24 months
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- Antigène
- Glypican 3 (GPC3)
- Autre désignation
- GPC3 (GPC3 Produits)
- Synonymes
- anticorps GPC3, anticorps sgb, anticorps dgsx, anticorps sdys, anticorps sgbs, anticorps oci-5, anticorps sgbs1, anticorps DGSX, anticorps GTR2-2, anticorps MXR7, anticorps OCI-5, anticorps SDYS, anticorps SGB, anticorps SGBS, anticorps SGBS1, anticorps Glypican-3, anticorps glypican 3, anticorps gpc3, anticorps GPC3, anticorps Gpc3
- Sujet
- Glypican-3 (GPC3) is a glycosylphospatidyl inositol-anchored membrane protein, which may also be found in a secreted form. Anti-GPC3 has been identified as a useful tumor marker for the diagnosis of hepatocellular carcinoma (HCC), hepatoblastoma, melanoma, testicular germ cell tumors, and Wilms tumor and hepatoblastoma, with a low or undetectable expression in normal adjacent tissue. In patients with thyroid cancer, expression of GPC3 is dramatically enhanced in certain types of cancers: 100 % in follicular carcinoma and 70 % in papillary carcinoma. Expression of GPC3 in follicular carcinoma is significantly higher than that of follicular adenoma. In contrast, GPC3 is not expressed in anaplastic carcinoma.
- Poids moléculaire
- 67kDa
- ID gène
- 2719
- UniProt
- P51654
- Pathways
- Glycosaminoglycan Metabolic Process
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