IGKC anticorps (CF®488A)

N° du produit ABIN6934406

Détail du produit anti-IGKC anticorps (CF®488A)

Antigène: IGKC (Immunoglobulin kappa Constant (IGKC))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IGKC est conjugé à/à la CF®488A

Application: Immunohistochemistry (IHC), Staining Methods (StM), Flow Cytometry (FACS)

Specificité: This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. It recognizes human Ig kappa light chains of both secreted and cell surface immunoglobulin. It detects also free kappa light chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Purification: Purified by Protein A/G

Immunogène: Recombinant full-length human IGKC protein

Clone: KLC709

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Positive Control: 293T, Raji or hPBL cells. Tonsil or Spleen.

Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunohistochemistry (Formalin-fixed) (0.5-1.0 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 100 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 4 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur IGKC

Antigène: IGKC (Immunoglobulin kappa Constant (IGKC))

Autre désignation: IGKC (IGKC Produits)

Synonymes: anticorps HCAK1, anticorps IGKCD, anticorps Km, anticorps IGKC, anticorps Igk-C, anticorps immunoglobulin kappa constant, anticorps immunoglobulin kappa constant L homeolog, anticorps IGKC, anticorps LOC708048, anticorps igkc, anticorps igkc.L, anticorps Igkc

Poids moléculaire: ~22.5kDa

ID gène: 3514

UniProt: P01601, P01834