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IgL anticorps (CF®488A)

Reactivité: Humain FACS, IF, T Hôte: Souris Monoclonal HP6054 CF®488A
N° du produit ABIN6934794
  • Antigène Tous les produits IgL
    IgL
    Reactivité
    Humain
    Hôte
    • 9
    • 3
    Souris
    Clonalité
    • 11
    • 1
    Monoclonal
    Conjugué
    • 12
    Cet anticorp IgL est conjugé à/à la CF®488A
    Application
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    Flow Cytometry (FACS), Immunofluorescence (IF), Test (T)
    Specificité
    This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
    Purification
    Purified by Protein A/G
    Immunogène
    Purified human IgG myeloma proteins coupled to polyaminostyren microbeads
    Clone
    HP6054
    Isotype
    IgG2a kappa
  • Indications d'application

    Positive Control: 293T, Raji or hPBL cells. Tonsil or Spleen.

    Known Application: Flow Cytometry (5 µL per test per one million cells or 5 µL per 100 µL of whole blood),Immunofluorescence (1:50-1:100),Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    100 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA and 0.05 % azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Antibody with azide - store at 4 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Date de péremption
    24 months
  • Antigène
    IgL
    Abstract
    IgL Produits
    Synonymes
    anticorps IGL@, anticorps IGLC6, anticorps igl, anticorps immunoglobulin lambda locus, anticorps IGL, anticorps igl@
    Poids moléculaire
    ~22.5kDa
    ID gène
    3535, 3546
    UniProt
    P01701, P01842
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