AMPD3 anticorps
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- Antigène Voir toutes AMPD3 Anticorps
- AMPD3 (Adenosine Monophosphate Deaminase 3 (AMPD3))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp AMPD3 est non-conjugé
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Application
- Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Specificité
- It recognizes a protein of ~90 kDa, which is identified as Adenosine Monophosphate Deaminase, isoform E (AMPD3). It has 767 amino acids and is assigned an EC 3.5.4.6. It is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. AMPD3 gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. This MAb shows reactivity with cells of the erythroid lineage at all stages of maturation in the peripheral blood, bone marrow, and fetal liver. Non-erythroid lineages are negative by flow cytometry. This MAb is useful in the diagnosis of erythroleukemia, identification of bone marrow erythroid precursors, gating erythroid nucleated precursor cells from malignant cells in bone marrow specimens.
- Réactivité croisée (Details)
- Human.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogène
- Recombinant full-length human AMDP3 protein
- Clone
- AMPD3-901
- Isotype
- IgG2b kappa
- Top Product
- Discover our top product AMPD3 Anticorps primaire
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- Indications d'application
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Known_Application: Immunohistochemistry (Formalin-fixed) (2-4 μg/mL for 30 minutes at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: RBC. Fetal liver, Spleen or Placenta.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Agent conservateur
- Azide free
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Date de péremption
- 24 months
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- Antigène
- AMPD3 (Adenosine Monophosphate Deaminase 3 (AMPD3))
- Autre désignation
- AMPD3 (AMPD3 Produits)
- Synonymes
- anticorps ampd3, anticorps fi25h10, anticorps wu:fi25h10, anticorps zgc:55390, anticorps MGC108215, anticorps adenosine monophosphate deaminase 3, anticorps adenosine monophosphate deaminase 3b, anticorps AMP deaminase 3, anticorps AMPD3, anticorps ampd3b, anticorps PTRG_08116, anticorps ampd3, anticorps Ampd3
- Sujet
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Adenosine monophosphate deaminase (isoform E), AMP aminohydrolase, AMP deaminase 3, AMP deaminase isoform E, Ampd3, Erythrocyte AMP deaminase, Erythrocyte specific AMP deaminase, Erythrocyte specific protein, Erythrocyte type AMP deaminase, Myoadenylate deaminase,AMP Deaminase, Isoform E (AMPD3) (Erythroid Marker)
Cellular localisation: Cell Surface - Poids moléculaire
- ~90kDa
- ID gène
- 272, 501890
- UniProt
- Q01432
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