CD207 anticorps (AA 74-213)
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- Antigène Voir toutes CD207 Anticorps
- CD207 (CD207 Molecule, Langerin (CD207))
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Épitope
- AA 74-213
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD207 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Coating (Coat)
- Specificité
- Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immuno-stimulatory capacity and play a central role in the initiation and regulation of immune responses. Langerin (CD207) is a Ca2+-dependent, C-type lectin domain containing, type II transmembrane protein that induces epidermal LCs to differentiate into Birbeck granules (BG). BGs are organelles with superimposing and zippering membranes that influence proper class I type antigen presentation to the circulating T cells. Human spleen, lymph node, thymus, liver, lung and heart express Langerin protein.
- Réactivité croisée (Details)
- Human.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogène
- Recombinant fragment (around aa74-213) of human Langerin protein (exact sequence is proprietary)
- Clone
- LGRN-1821
- Isotype
- IgG2a kappa
- Top Product
- Discover our top product CD207 Anticorps primaire
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- Indications d'application
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Known_Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or A549 cells (WB).
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Agent conservateur
- Azide free
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Date de péremption
- 24 months
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- Antigène
- CD207 (CD207 Molecule, Langerin (CD207))
- Autre désignation
- CD207 (CD207 Produits)
- Synonymes
- anticorps CD207, anticorps CLEC4K, anticorps RGD1565913, anticorps CD207 molecule, anticorps CD207 antigen, anticorps CD207, anticorps Cd207
- Sujet
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C-type lectin domain family 4 member K, CD207, CLEC4K, Langerhans cell specific c type lectin, Langerin,Langerin / CD207 (Marker of Langerhans Cells)
Cellular localisation: Cell surface and cytoplasmic - Poids moléculaire
- 48kDa
- ID gène
- 50489, 199731
- UniProt
- Q9UJ71
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