Recombinant Elastin anticorps

N° du produit ABIN6937144

Détail du produit anti-Elastin anticorps

Antigène: Elastin (ELN)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Elastin est non-conjugé

Application: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Specificité: Elastin is a polymeric protein and is the main component of the extracellular matrix of arteries.It is synthesized and secreted as a soluble, single-chain protein (tropoelastin), which undergoes a number of post-translational modifications prior to its organization into an elastic fiber in the extracellular space. Elastin performs a regulatory function during arterial development by controlling proliferation of smooth muscle and stabilizing arterial structure. It imparts elasticityto the connective tissue. During aging, the elasticity of connective tissue is reduced because of the cross-linking of collagenous fibers with elastin. The abnormal accumulation of elastic tissue in blood vessels is found in atherosclerosis and hypertension.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant full-length human Elastin protein

Clone: ELN-3131R

Isotype: IgG

Information d'application

Indications d'application:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Positive_Control: A549 or U-2197 cells. Liver, Kidney, Lung or Intestine.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur Elastin

Antigène: Elastin (ELN)

Autre désignation: ELN (ELN Produits)

Synonymes: anticorps SVAS, anticorps WBS, anticorps WS, anticorps AI385707, anticorps AI480567, anticorps E030024M20Rik, anticorps RATTREL11, anticorps TREL11, anticorps Trela, anticorps Trela26, anticorps ELN, anticorps elastin, anticorps ELN, anticorps Eln, anticorps LOC574132, anticorps Tcur_2481, anticorps Kfla_2289, anticorps LOC100620140

Sujet: Elastin, ELN, SVAS, Tropoelastin, WBS, WS,Elastin (ELN) (Marker of Arterial Stiffness and Atherosclerosis)
Cellular localisation: Secreted and Extracellular Space

Poids moléculaire: 70kDa

ID gène: 2006, 647061

UniProt: P15502

Pathways: Regulation of Actin Filament Polymerization