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Recombinant Growth Hormone 1 anticorps (AA 58-187)

GH1 Reactivité: Humain IHC, IHC (f) Hôte: Souris Monoclonal rGH-1450 unconjugated Recombinant Antibody
N° du produit ABIN6937317
  • Antigène Voir toutes Growth Hormone 1 (GH1) Anticorps
    Growth Hormone 1 (GH1)
    Type d'anticorp
    Recombinant Antibody
    Épitope
    • 18
    • 13
    • 8
    • 6
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 58-187
    Reactivité
    • 105
    • 18
    • 13
    • 9
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 70
    • 53
    • 2
    • 1
    • 1
    Souris
    Clonalité
    • 64
    • 63
    Monoclonal
    Conjugué
    • 77
    • 11
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Growth Hormone 1 est non-conjugé
    Application
    • 71
    • 48
    • 37
    • 20
    • 20
    • 15
    • 14
    • 13
    • 13
    • 11
    • 9
    • 7
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Specificité
    Pituitary growth hormone (GH) plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Anti-GH is a useful marker in classification of pituitary tumors and the study of pituitary disease (acromegaly).
    Réactivité croisée (Details)
    Human.
    Purification
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogène
    A recombinant fragment (around aa58-187) of human Growth Hormone (GH) protein (exact sequence is proprietary)
    Clone
    RGH-1450
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product GH1 Anticorps primaire
  • Indications d'application

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: Pituitary cells. Human pituitary tissue (IHC).

    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Agent conservateur
    Azide free
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Date de péremption
    24 months
  • Antigène
    Growth Hormone 1 (GH1)
    Autre désignation
    GH1 (GH1 Produits)
    Synonymes
    anticorps GH, anticorps GH-N, anticorps GHN, anticorps IGHD1B, anticorps hGH-N, anticorps Gh1, anticorps GH1, anticorps gh, anticorps Gh, anticorps GH2, anticorps RNGHGP, anticorps ghl, anticorps gh-n, anticorps ghn, anticorps ighd1b, anticorps gh1, anticorps ghb-A, anticorps GHI, anticorps GHB3, anticorps growth hormone 1, anticorps growth hormone, anticorps somatotropin-like, anticorps somatotropin, anticorps growth hormone prepeptide, anticorps growth hormone 1 L homeolog, anticorps growth hormone 1 S homeolog, anticorps Somatotropin-1, anticorps GH1, anticorps Gh, anticorps GH, anticorps LOC100305005, anticorps Gh1, anticorps LOC100534452, anticorps LOC100232594, anticorps LOC100303681, anticorps gh1, anticorps LOC100356068, anticorps LOC100136588, anticorps gh1.L, anticorps gh1.S, anticorps LOC109081196
    Sujet
    GH, GH-N, GH1, GHN, Growth hormone 1, Growth hormone, Growth hormone, pituitary, HG1, hGH-N, IGHD1B, Pituitary growth hormone, RNGHGP, Somatotropin,Growth Hormone (Pituitary Marker)
    Cellular localisation: Cytoplasmic
    Poids moléculaire
    20kDa
    ID gène
    2688, 655229
    UniProt
    P01241
    Pathways
    Signalisation NF-kappaB, Signalistation JAK/STAT, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Response to Growth Hormone Stimulus, Regulation of Hormone Biosynthetic Process
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