GPN1 anticorps

N° du produit ABIN6937346

Détail du produit anti-GPN1 anticorps

Antigène: GPN1 (GPN-Loop GTPase 1 (GPN1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GPN1 est non-conjugé

Application: Western Blotting (WB), ELISA, Coating (Coat)

Specificité: GPN1 is involved in protein synthesis events. It is expressed ubiquitously with highest expression in testis. It binds to the RNA polymerase II- (Poll II) associated proteins RPAP1-3 and to XPA (a protein involved in DNA repair mechanisms), thereby forming an interface with Poll II. Via this interaction, GPN1 is thought to mediate the involvement of Pol II in both protein complex formation and protein chaperone/ scaffolding activities. In addition, GPN1 interacts with components of the integrator and molecular chaperone complexes, further implicating GPN1 in protein assembly. GPN1 contains a cluster of acidic amino acids in its C-terminal region and a series of sequences similar to those found in GTP-binding proteins in its N-terminal region, suggesting that GPN1 has possible GTPase activity.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant full-length human GPN1 protein

Clone: GPN1-2350

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Known_Application: ELISA (For coating, order antibody without BSA), Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Positive_Control: Pancreas, Testis, Thyroid or Bladder.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur GPN1

Antigène: GPN1 (GPN-Loop GTPase 1 (GPN1))

Autre désignation: GPN1 (GPN1 Produits)

Sujet: ATP(GTP) binding protein (ATPBD1A), GPN-loop GTPase 1, GPN1, MBD2-interacting protein (MBDin), NTPBP, RNA polymerase II associated protein 4 (RPAP4), XPA-binding protein 1 (XAB1) GTPase,GPN1 / XAB1 (DNA Repair & Protein Synthesis)
Cellular localisation: Cytoplasmic & Nuclear

Poids moléculaire: 42kDa

ID gène: 11321, 18259