IFNA1 anticorps
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- Antigène Voir toutes IFNA1 Anticorps
- IFNA1 (Interferon, alpha 1 (IFNA1))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp IFNA1 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificité
- This MAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.
- Réactivité croisée (Details)
- Human.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogène
- Purified recombinant human IFN-alpha1
- Clone
- Feb-48
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product IFNA1 Anticorps primaire
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- Indications d'application
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Known_Application: Flow Cytometry (1-2 μg/million cells), Western Blot (1-2 μg/mL), Immunohistochemistry (frozen), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.
Positive_Control: Stimulated human peripheral blood mononuclear cells.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Agent conservateur
- Azide free
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Date de péremption
- 24 months
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- Antigène
- IFNA1 (Interferon, alpha 1 (IFNA1))
- Autre désignation
- IFNA1 (IFNA1 Produits)
- Synonymes
- anticorps IFL, anticorps IFN, anticorps IFN-ALPHA, anticorps IFN-alphaD, anticorps IFNA13, anticorps IFNA@, anticorps Ifa1, anticorps IFN-ALPHA-1, anticorps IFN1@, anticorps IFNA1, anticorps IFN-alpha, anticorps IFN-gamma, anticorps IFNA, anticorps IFNA2, anticorps IFNA6, anticorps IFN-alpha1, anticorps interferon alpha 13, anticorps interferon alpha 1, anticorps interferon, alpha 1, anticorps interferon, alpha 13, anticorps interferon, anticorps interferon-alpha 1, anticorps interferon, alpha, leukocyte, anticorps interferon-alpha-14, anticorps IFNA13, anticorps IFNA1, anticorps Ifna1, anticorps ifna1, anticorps IFNA3, anticorps IFN-ALPHA-14
- Sujet
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IFN alpha, IFN alpha 1/13, IFN alpha 1b, Interferon alpha 13 (IFNA13), Interferon alpha leukocyte (IFL), Interferon alpha-1/13 (IFN-alpha-1/13), Interferon alpha-D (IFN alphaD), Interferon alpha1 (IFNA1), LeIF D,Interferon alpha-1 (IFNA1)
Cellular localisation: Cytoplasmic & Extracellular (Secreted) - Poids moléculaire
- 16-27kDa
- ID gène
- 3439, 37026, 533471
- UniProt
- P01562
- Pathways
- Signalistation JAK/STAT, Hepatitis C
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