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IGHG anticorps

IGHG Reactivité: Humain IHC, FACS, IF, IHC (p) Hôte: Souris Monoclonal IG217 unconjugated
N° du produit ABIN6937497
  • Antigène Tous les produits IGHG
    IGHG (Immunoglobulin Heavy Chain (Gamma Polypeptide) (IGHG))
    Reactivité
    • 15
    • 2
    Humain
    Hôte
    • 8
    • 7
    • 2
    Souris
    Clonalité
    • 15
    • 2
    Monoclonal
    Conjugué
    • 15
    • 1
    • 1
    Cet anticorp IGHG est non-conjugé
    Application
    • 10
    • 10
    • 7
    • 6
    • 6
    • 4
    • 4
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificité
    Recognizes a protein of 75kDa, identified as gamma heavy chain of human immunoglobulins. It reacts with all sub-classes of gamma chain of human immunoglobulins. It does not cross-react with alpha (IgA), mu (IgM), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This MAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
    Réactivité croisée (Details)
    Human.
    Purification
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogène
    Purified human Ig Gamma Chain
    Clone
    IG217
    Isotype
    IgG1 kappa
  • Indications d'application

    Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin/paraffin) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: 293T, Raji or hPBL cells. Tonsil or Spleen.

    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Agent conservateur
    Azide free
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Date de péremption
    24 months
  • Antigène
    IGHG (Immunoglobulin Heavy Chain (Gamma Polypeptide) (IGHG))
    Autre désignation
    IGHG (IGHG Produits)
    Synonymes
    anticorps AU044919, anticorps IGHG2A, anticorps Immunoglobulin heavy chain (gamma polypeptide), anticorps Ighg
    Sujet
    G1m Marker, G2m Marker, G3m Marker, G4m Marker, HDC, Heavy Chain Disease Protein, Human Immunglobulin G, Ig gamma1/2/3/4 Chain C Region, IGHG1, IGHG2, IGHG3, IGHG4, Immunoglobulin Heavy Constant 1/2/3/4,IgG (Immunoglobulin Gamma Heavy Chain) (B-Cell Marker)
    Cellular localisation: Cytoplasm, Cell Surface and Secreted
    Poids moléculaire
    75kDa
    ID gène
    3500, 3501, 3502
    UniProt
    P01857, P01859, P01860, P01861
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