Recombinant KRT6A anticorps
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- Antigène Voir toutes KRT6A Anticorps
- KRT6A (Keratin 6A (KRT6A))
- Type d'anticorp
- Recombinant Antibody
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp KRT6A est non-conjugé
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Application
- Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Specificité
- This MAb recognizes a protein of 56 kDa, identified as cytokeratin 6A (KRT6A). In humans, multiple isoforms of Cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns. Cytokeratin 6A is the dominant form in epithelial tissue. Cytokeratin 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyper-proliferation-related keratins). Cytokeratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyper-proliferative situations. Epidermal injury results in activation of keratinocytes, which express KRT6 and KRT16. KRT6 is strongly expressed in about 75 % of head and neck squamous cell carcinomas.
- Réactivité croisée (Details)
- Human.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogène
- Recombinant full-length human Cytokeratin 6A (KRT6A) protein
- Clone
- RKRT6A-2100
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product KRT6A Anticorps primaire
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- Indications d'application
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: Tonsil or basal cell carcinoma.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Agent conservateur
- Azide free
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Date de péremption
- 24 months
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- Antigène
- KRT6A (Keratin 6A (KRT6A))
- Autre désignation
- KRT6A (KRT6A Produits)
- Synonymes
- anticorps CK6A, anticorps CK6C, anticorps CK6D, anticorps K6A, anticorps K6C, anticorps K6D, anticorps KRT6C, anticorps KRT6D, anticorps 2310016L08Rik, anticorps Krt2-6a, anticorps Krt2-6c, anticorps MK6a, anticorps mK6[a], anticorps CK-6A, anticorps Krt6a, anticorps KRT6A, anticorps keratin 6A, anticorps similar to keratin complex 2, basic, gene 6a, anticorps keratin, type II cytoskeletal 6A, anticorps KRT6A, anticorps Krt6a, anticorps LOC683313, anticorps LOC101112304
- Sujet
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58 kDa Cytokeratin, CK5, Cytokeratin-5, DDD1, Epidermolysis Bullosa Simplex 2 (EBS2), Keratin 5, Keratin, Type II Cytoskeletal 5, Keratin-5, KRT5, Type-II Cytoskeletal 5, Type-II keratin Kb5,Cytokeratin 6A (KRT6A) (Basal Cell Marker)
Cellular localisation: Cytoplasmic - Poids moléculaire
- 58kDa
- ID gène
- 3853, 700779
- UniProt
- P02538
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