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Macrophage / Histiocytoma Marker anticorps

Reactivité: Humain IHC, StM Hôte: Souris Monoclonal D11 unconjugated
N° du produit ABIN6937792
  • Antigène Tous les produits Macrophage / Histiocytoma Marker
    Macrophage / Histiocytoma Marker
    Reactivité
    Humain
    Hôte
    • 2
    Souris
    Clonalité
    • 2
    Monoclonal
    Conjugué
    • 2
    Cet anticorp Macrophage / Histiocytoma Marker est non-conjugé
    Application
    Immunohistochemistry (IHC), Staining Methods (StM)
    Specificité
    In Western blotting, it detects an antigen of 125 kDa in human liver and 135 kDa in tumors of histiocytic origin. Comparative study of this MAb and a standard CD68 MAb showed that their antigens are different. Its antigen in all macrophage types studied is located on the plasma membrane and within cytoplasmic structures including lysosomes. This MAb shows a restricted reactivity to cells of the monocyte/macrophage system. It specifically reacts with blood monocytes and stains resident macrophages in a wide variety of human tissues. This MAb does not stain antigen-presenting cells, e.g., Langerhans cells. Reportedly, its reactivity is restricted to histiocytes and macrophages.
    Aucune reactivité croisée
    Souris, Porc, Rat (Rattus)
    Purification
    Purified by Protein A/G
    Immunogène
    Membrane preparation from human hepatocytes
    Clone
    D11
    Isotype
    IgG1 kappa
  • Indications d'application

    Positive Control: Liver or Histiocytoma.

    Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Buffer
    10 mM PBS without BSA and without Azide.
    Agent conservateur
    Azide free
    Stock
    4 °C,-80 °C
    Stockage commentaire
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months.
    Date de péremption
    24 months
  • Antigène
    Macrophage / Histiocytoma Marker
    Autre désignation
    Macrophage & Histiocytoma Marker (Macrophage / Histiocytoma Marker Produits)
    Poids moléculaire
    125kDa -135kDa
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