Myogenin anticorps (AA 30-224)
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- Antigène Voir toutes Myogenin (MYOG) Anticorps
- Myogenin (MYOG) (Myogenin (Myogenic Factor 4) (MYOG))
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Épitope
- AA 30-224
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Reactivité
- Humain, Rat
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Myogenin est non-conjugé
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Application
- Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Specificité
- Myogenin is a member of the MyoD family of myogenic basic helix-loop-helix (bHLH) transcription factors that also includes MyoD, Myf-5, and MRF4 (also known as herculinor Myf-6). MyoD family members are expressed exclusively in skeletal muscle and play a key role in activating myogenesis by binding to enhancer sequences of muscle-specific genes. The regulatory domain of MyoD is approximately 70 amino acids in length and includes both a basic DNA binding motif and a bHLH dimerization motif.MyoD family members share about 80% amino acid homology in their bHLH motifs.Anti-myogenin labels the nuclei of myoblasts in developing muscle tissue, and is expressed in tumor cell nuclei of rhabdomyosarcoma and some leiomyosarcomas. Positive nuclear staining may occur in Wilms' tumor.
- Réactivité croisée (Details)
- Human. Mouse. Rat. Cat. Pig.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogène
- Human myogenin recombinant protein (MGN185), Rat myogenin recombinant fragment containing amino acid 30-224 (F5D)
- Clone
- MGN185-F5D
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product MYOG Anticorps primaire
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- Indications d'application
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: Rh-30 cells. Skeletal muscle or rhabdomyosarcoma.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Agent conservateur
- Azide free
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Date de péremption
- 24 months
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- Antigène
- Myogenin (MYOG) (Myogenin (Myogenic Factor 4) (MYOG))
- Autre désignation
- MYOG (MYOG Produits)
- Synonymes
- anticorps cb553, anticorps zgc:100763, anticorps LOC446037, anticorps myf4, anticorps Xmyog, anticorps myogenin, anticorps LOC100136471, anticorps LOC100224062, anticorps LOC100303673, anticorps MYF4, anticorps bHLHc3, anticorps myo, anticorps myf-4, anticorps myogenin, anticorps myogenin (myogenic factor 4), anticorps MYOG, anticorps myog, anticorps LOC100303673, anticorps Myog
- Sujet
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BHLHc3, cb553, Class C basic helix-loop-helix protein 3, Myf-4, MYF4, MYOG, Myogenic factor 4,Myogenin / Myf-4 (Skeletal Muscle Marker)
Cellular localisation: Nuclear - Poids moléculaire
- 34kDa
- ID gène
- 4656, 2830
- UniProt
- P15173
- Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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