p63 anticorps (AA 3-106)
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- Antigène Voir toutes p63 (TP63) Anticorps
- p63 (TP63) (Tumor Protein P63 (TP63))
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Épitope
- AA 3-106
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp p63 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Coating (Coat)
- Specificité
- P63 is a homolog of the tumor suppressor p53. It is identified in basal cells in the epithelial layers of a variety of tissues, including epidermis, cervix, urothelium, breast and prostate. p63 was detected in nuclei of the basal epithelium in normal prostate glands, however, it was not expressed in malignant tumors of the prostate. As a result, p63 has been reported as a useful marker for differentiating benign from malignant lesions in the prostate, particularly when used in combination with markers of high molecular weight cytokeratins and the prostate-specific marker AMACR (P504S). p63 has also been shown to be a sensitive marker for lung squamous cell carcinomas (SqCC), with a sensitivity of ~90 % . Specificity for lung SqCC, vs. lung adenocarcinoma (LADC), is approximately 80 %. In breast tissue, p63 has been identified in myoepithelial cells of normal ducts.
- Réactivité croisée (Details)
- Human.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogène
- Recombinant fragment (around aa 3-106) of human p63 protein (exact sequence is proprietary)
- Clone
- TP63-1786
- Isotype
- IgG2b kappa
- Top Product
- Discover our top product TP63 Anticorps primaire
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- Indications d'application
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Known_Application: ELISA (For coating, order Ab without BSA),Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.
Positive_Control: HEK293 cells. Prostate Carcinoma or Lung or bladder squamous cell carcinoma.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Agent conservateur
- Azide free
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Date de péremption
- 24 months
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- Antigène
- p63 (TP63) (Tumor Protein P63 (TP63))
- Autre désignation
- TP63 (TP63 Produits)
- Synonymes
- anticorps AIS, anticorps B(p51A), anticorps B(p51B), anticorps EEC3, anticorps KET, anticorps LMS, anticorps NBP, anticorps OFC8, anticorps RHS, anticorps SHFM4, anticorps TP53CP, anticorps TP53L, anticorps TP73L, anticorps p40, anticorps p51, anticorps p53CP, anticorps p63, anticorps p73H, anticorps p73L, anticorps TP63, anticorps tp63, anticorps DNp63, anticorps id:ibd3516, anticorps tp73l, anticorps wu:fc89f04, anticorps wu:fk85h07, anticorps wu:fk88b02, anticorps Ket, anticorps P73l, anticorps Tp73l, anticorps Trp63, anticorps TRP63, anticorps AI462811, anticorps P51/P63, anticorps P63, anticorps Tp63, anticorps Trp53rp1, anticorps Xp63, anticorps ket, anticorps np63, anticorps tp73l-A, anticorps trp63, anticorps tumor protein p63, anticorps transformation related protein 63, anticorps tumor protein p63 L homeolog, anticorps TP63, anticorps tp63, anticorps Tp63, anticorps Trp63, anticorps tp63.L
- Sujet
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Amplified in squamous cell carcinoma (AIS), Chronic ulcerative stomatitis protein (CUSP), EEC3, Keratinocyte transcription factor KET, LMS, NBP, p40, P51/P63, p53 like transcription factor, p53-related protein p63, RHS, SHFM4, TAp63alpha, TP53CP, TP53L, TP63, TP73, TP73L, Transformation-related protein 63, Trp53rp1, Trp6,3, Tumor protein 63, Tumor protein p53-like, tumor protein p73-like,p63 (Squamous, Basal & Myoepithelial Cell Marker)
Cellular localisation: Nuclear - Poids moléculaire
- 63kDa
- ID gène
- 8626, 137569
- UniProt
- Q9H3D4
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