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LI Cadherin anticorps (AA 242-418)

Reactivité: Humain WB, IHC (f) Hôte: Souris Monoclonal CDH17-2617 unconjugated
N° du produit ABIN6939028
  • Antigène Voir toutes LI Cadherin Anticorps
    LI Cadherin
    Épitope
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 242-418
    Reactivité
    • 40
    • 9
    • 7
    • 7
    Humain
    Hôte
    • 28
    • 12
    Souris
    Clonalité
    • 27
    • 12
    • 1
    Monoclonal
    Conjugué
    • 30
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp LI Cadherin est non-conjugé
    Application
    • 27
    • 18
    • 14
    • 7
    • 7
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Specificité
    It recognizes a protein of 120 kDa, which is identified as Cadherin 17 (also known as LI Cadherin). The cadherins are a family of Calcium-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including beta-catenin, to regulate cadherin function. LI-cadherin (for liver-intestine-cadherin) expression is restricted to liver and intestine tissues and is specifically localized to the basolateral domain of hepatocytes and enterocytes.
    Réactivité croisée (Details)
    Human,
    Purification
    200ug/ml of Ab Purified from rabbit anti-serum by Protein A.
    Immunogène
    Recombinant fragment (around aa 242-418) of human Cadherin 17 protein (CDH17) (exact sequence is proprietary)
    Clone
    CDH17-2617
    Isotype
    IgG2b
    Top Product
    Discover our top product LI Cadherin Anticorps primaire
  • Indications d'application

    Positive Control: HepG2 or HT29 cells. Stomach, Small Intestine, Colon or liver.

    Known Application: Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-80 °C
    Stockage commentaire
    Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.
    Date de péremption
    24 months
  • Antigène
    LI Cadherin
    Autre désignation
    CDH17 (LI Cadherin Produits)
    Synonymes
    anticorps CDH16, anticorps HPT-1, anticorps HPT1, anticorps HPT-1/LI, anticorps cb903, anticorps fb65d02, anticorps wu:fb65d02, anticorps cadherin-17, anticorps cadherin 17, anticorps cadherin 17, LI cadherin (liver-intestine), anticorps CDH17, anticorps Cdh17, anticorps cdh17
    Sujet
    BILL-cadherin, Cadherin-17, CDH17, HPT-1 cadherin, human intestinal peptide-associated transporter HPT-1, human peptide transporter 1 (HPT-1), Intestinal peptide-associated transporter HPT-1, LI-cadherin (liver-intestine), Liver Cadherin, Liver-intestine cadherin,Cadherin 17 / LI Cadherin (Liver-Intestine Marker)
    Cellular localisation: Cell Surface and Cytoplasmic
    Poids moléculaire
    120kDa
    ID gène
    1015, 591853
    UniProt
    Q12864
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