LI Cadherin anticorps (AA 242-418)
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- Antigène Voir toutes LI Cadherin Anticorps
- LI Cadherin
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Épitope
- AA 242-418
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp LI Cadherin est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Specificité
- It recognizes a protein of 120 kDa, which is identified as Cadherin 17 (also known as LI Cadherin). The cadherins are a family of Calcium-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including beta-catenin, to regulate cadherin function. LI-cadherin (for liver-intestine-cadherin) expression is restricted to liver and intestine tissues and is specifically localized to the basolateral domain of hepatocytes and enterocytes.
- Réactivité croisée (Details)
- Human,
- Purification
- 200ug/ml of Ab Purified from rabbit anti-serum by Protein A.
- Immunogène
- Recombinant fragment (around aa 242-418) of human Cadherin 17 protein (CDH17) (exact sequence is proprietary)
- Clone
- CDH17-2617
- Isotype
- IgG2b
- Top Product
- Discover our top product LI Cadherin Anticorps primaire
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- Indications d'application
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Positive Control: HepG2 or HT29 cells. Stomach, Small Intestine, Colon or liver.
Known Application: Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
- Restrictions
- For Research Use only
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- Concentration
- 200 μg/mL
- Buffer
- Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-80 °C
- Stockage commentaire
- Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.
- Date de péremption
- 24 months
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- Antigène
- LI Cadherin
- Autre désignation
- CDH17 (LI Cadherin Produits)
- Synonymes
- anticorps CDH16, anticorps HPT-1, anticorps HPT1, anticorps HPT-1/LI, anticorps cb903, anticorps fb65d02, anticorps wu:fb65d02, anticorps cadherin-17, anticorps cadherin 17, anticorps cadherin 17, LI cadherin (liver-intestine), anticorps CDH17, anticorps Cdh17, anticorps cdh17
- Sujet
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BILL-cadherin, Cadherin-17, CDH17, HPT-1 cadherin, human intestinal peptide-associated transporter HPT-1, human peptide transporter 1 (HPT-1), Intestinal peptide-associated transporter HPT-1, LI-cadherin (liver-intestine), Liver Cadherin, Liver-intestine cadherin,Cadherin 17 / LI Cadherin (Liver-Intestine Marker)
Cellular localisation: Cell Surface and Cytoplasmic - Poids moléculaire
- 120kDa
- ID gène
- 1015, 591853
- UniProt
- Q12864
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