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UPK1A anticorps (AA 114-173)

UPK1A Reactivité: Humain ELISA, Coat, IHC (f) Hôte: Souris Monoclonal UPK1A-2921 unconjugated
N° du produit ABIN6939114
  • Antigène Voir toutes UPK1A Anticorps
    UPK1A (Uroplakin 1a (UPK1A))
    Épitope
    • 8
    • 8
    • 7
    • 4
    • 1
    • 1
    AA 114-173
    Reactivité
    • 21
    • 3
    • 1
    Humain
    Hôte
    • 19
    • 4
    Souris
    Clonalité
    • 19
    • 4
    Monoclonal
    Conjugué
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp UPK1A est non-conjugé
    Application
    • 18
    • 16
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    ELISA, Coating (Coat), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Specificité
    The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The protein may also play a role in tumor suppression.
    Réactivité croisée (Details)
    Human,
    Purification
    200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
    Immunogène
    Recombinant fragment (around aa 114-173) of human Uroplakin 1A (UPK1A) protein (exact sequence is proprietary)
    Clone
    UPK1A-2921
    Isotype
    IgG2b
  • Indications d'application

    Positive Control: Urinary Bladder.

    Known Application: ELISA (For coating, order Ab without BSA), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-80 °C
    Stockage commentaire
    Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.
    Date de péremption
    24 months
  • Antigène
    UPK1A (Uroplakin 1a (UPK1A))
    Autre désignation
    UPK1A (UPK1A Produits)
    Synonymes
    anticorps up1a, anticorps upia, anticorps upka, anticorps tspan21, anticorps MGC81390, anticorps upk1a, anticorps MGC69509, anticorps UPK1A, anticorps wu:fb14a02, anticorps wu:fk84c04, anticorps zgc:136832, anticorps TSPAN21, anticorps UP1A, anticorps UPIA, anticorps UPKA, anticorps 1110031P12Rik, anticorps AU019298, anticorps C87192, anticorps Tspan21, anticorps Upk1, anticorps uroplakin 1A, anticorps uroplakin 1A L homeolog, anticorps uroplakin 1a, anticorps UPK1A, anticorps upk1a.L, anticorps upk1a, anticorps Upk1a
    Sujet
    UP1A, UPIA, UPKA, TSPAN21,Uroplakin 1A (Urothelial Differentiation Marker)
    Cellular localisation: Cell Surface
    Poids moléculaire
    29kDa
    ID gène
    11045, 159309
    UniProt
    O00322
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