Chromogranin A anticorps

N° du produit ABIN6939121

Détail du produit anti-Chromogranin A anticorps

Antigène: Chromogranin A (CHGA)

Reactivité: Humain, Rat, Souris, Singe, Porc

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Chromogranin A est non-conjugé

Application: Immunohistochemistry (IHC), Staining Methods (StM)

Specificité: Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.

Purification: Purified by Protein A/G

Immunogène: Recombinant human chromogranin A protein

Clone: CGA-413-CHGA-777-CHGA-798

Isotype: IgG2b kappa

Information d'application

Indications d'application:

Positive Control: PC12 cells. Adrenal gland, bowel, thyroid, pancreas or pheochromocytoma.

Known Application: Immunohistochemistry (Formalin-fixed) (0.25-0.5 μg/mL for 30 minutes at RT) (Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur Chromogranin A

Antigène: Chromogranin A (CHGA)

Autre désignation: CHGA (CHGA Produits)

Synonymes: anticorps CGA, anticorps CG-ALPHA, anticorps FSHA, anticorps GPHA1, anticorps GPHa, anticorps HCG, anticorps LHA, anticorps TSHA, anticorps ChrA, anticorps fj05f09, anticorps si:dkey-177p2.2, anticorps wu:fj05f09, anticorps zgc:101749, anticorps zgc:56075, anticorps CHGA, anticorps cgA, anticorps chga, anticorps chromogranin A, anticorps glycoprotein hormones, alpha polypeptide, anticorps uncharacterized CHGA, anticorps chromogranin A S homeolog, anticorps CHGA, anticorps CGA, anticorps Chga, anticorps chga, anticorps chga.S

Poids moléculaire: 68-75kDa

ID gène: 1113

UniProt: P10645

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling