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TOP1MT anticorps

TOP1MT Reactivité: Humain IHC, StM Hôte: Souris Monoclonal TOP1MT-568 unconjugated
N° du produit ABIN6939148
  • Antigène Voir toutes TOP1MT Anticorps
    TOP1MT (Topoisomerase (DNA) I, Mitochondrial (TOP1MT))
    Reactivité
    • 28
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 19
    • 11
    Souris
    Clonalité
    • 17
    • 13
    Monoclonal
    Conjugué
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TOP1MT est non-conjugé
    Application
    • 11
    • 10
    • 10
    • 10
    • 6
    • 4
    • 2
    • 2
    Immunohistochemistry (IHC), Staining Methods (StM)
    Purification
    Purified by Protein A/G
    Immunogène
    Recombinant full-length human TOP1MT protein
    Clone
    TOP1MT-568
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product TOP1MT Anticorps primaire
  • Indications d'application

    Positive Control: A431 cells. Heart, Skeletal muscle, brain or fetal liver.

    Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-80 °C
    Stockage commentaire
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Date de péremption
    24 months
  • Antigène
    TOP1MT (Topoisomerase (DNA) I, Mitochondrial (TOP1MT))
    Autre désignation
    TOP1MT (TOP1MT Produits)
    Synonymes
    anticorps 2900052H09Rik, anticorps TOP1, anticorps topoisomerase (DNA) I, mitochondrial, anticorps DNA topoisomerase 1, mitochondrial, anticorps DNA topoisomerase I mitochondrial, anticorps TOP1MT, anticorps Top1mt
    Sujet
    DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.
    Poids moléculaire
    70kDa
    ID gène
    116447
    UniProt
    Q969P6
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