Angiotensin I Converting Enzyme 1 anticorps

N° du produit ABIN6939231

Détail du produit anti-Angiotensin I Converting Enzyme 1 anticorps

Antigène: Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Angiotensin I Converting Enzyme 1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Coating (Coat), Staining Methods (StM)

Purification: Purified by Protein A/G

Immunogène: Full-length recombinant human ACE/CD143 protein

Clone: 9B9

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Positive Control: Ubiquitously expressed, with highest levels in lung, kidney, heart, gastrointestinal system and prostate.

Known Application: ELISA (For coating, order antibody without BSA),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT) ,(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur Angiotensin I Converting Enzyme 1

Antigène: Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))

Autre désignation: ACE (ACE Produits)

Synonymes: anticorps ACE1, anticorps CD143, anticorps DCP, anticorps DCP1, anticorps ICH, anticorps MVCD3, anticorps AW208573, anticorps Dcp1, anticorps StsRR92, anticorps dcp, anticorps ace1, anticorps dcp1, anticorps xace, anticorps cd143, anticorps ACE, anticorps angiotensin I converting enzyme, anticorps angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, anticorps angiotensin-converting enzyme, anticorps angiotensin I converting enzyme (peptidyl-dipeptidase A) 3, anticorps angiotensin-converting enzyme-like, anticorps ACE, anticorps Ace, anticorps ace, anticorps CpipJ_CPIJ009106, anticorps ACE3, anticorps LOC101824864

Sujet: This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined.

Poids moléculaire: 195kDa

ID gène: 1636

UniProt: P12821

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration