Dystrophin anticorps (AA 114-263)
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- Antigène Voir toutes Dystrophin (DMD) Anticorps
- Dystrophin (DMD)
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Épitope
- AA 114-263
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Dystrophin est non-conjugé
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Application
- Immunohistochemistry (IHC), ELISA, Coating (Coat), Staining Methods (StM)
- Purification
- Purified by Protein A/G
- Immunogène
- A recombinant fragment (around aa 114-263) of human DMD protein (exact sequence is proprietary)
- Clone
- DMD-3242
- Isotype
- IgG2b kappa
- Top Product
- Discover our top product DMD Anticorps primaire
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- Indications d'application
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Positive Control: Human skeletal muscle and heart muscle tissues (IHC).
Known Application: ELISA (For coating, order Ab without BSA),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
- Restrictions
- For Research Use only
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- Concentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-80 °C
- Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Date de péremption
- 24 months
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- Antigène
- Dystrophin (DMD)
- Autre désignation
- DMD (DMD Produits)
- Synonymes
- anticorps DMD, anticorps Dmd, anticorps MGC83347, anticorps DKFZp459C1629, anticorps dmd, anticorps MGC79631, anticorps DKFZp468A1620, anticorps Dp71, anticorps cb664, anticorps zfDYS, anticorps im:6911785, anticorps zgc:110165, anticorps BMD, anticorps CMD3B, anticorps DXS142, anticorps DXS164, anticorps DXS206, anticorps DXS230, anticorps DXS239, anticorps DXS268, anticorps DXS269, anticorps DXS270, anticorps DXS272, anticorps DXSmh7, anticorps DXSmh9, anticorps Dp427, anticorps dys, anticorps mdx, anticorps pke, anticorps DNADMD1, anticorps RATDMD, anticorps CG17750, anticorps CG31175, anticorps CG34157, anticorps CG7240, anticorps CG7243, anticorps CG7344, anticorps DLP, anticorps DLP1, anticorps DLP186, anticorps DLP2, anticorps DLP3, anticorps DmDLP, anticorps DmDYS, anticorps Dmel\\CG34157, anticorps Dp117, anticorps Dp186, anticorps Dp205, anticorps GI3046716, anticorps IDLP, anticorps det, anticorps dmDLP, anticorps dmDp186, anticorps dmDys, anticorps dystrophin, anticorps dystrophin, gene 1 L homeolog, anticorps dystrophin, gene 1, anticorps dystrophin, muscular dystrophy, anticorps Dystrophin, anticorps DMD, anticorps LOC708073, anticorps dmd.1.L, anticorps LOC465557, anticorps dmd.1, anticorps dmd, anticorps Dmd, anticorps Dys
- Sujet
- Dystrophin-glycoprotein complex (DGC) connects the F-Actin cytoskeleton on the inner surface of muscle fibers to the surrounding extracellular matrix, through the cell membrane interface. A deficiency in this protein contributes to Duchenne (DMD) and Becker (BMD) muscular dystrophies. The human dystrophin gene measures 2.4 megabases, has more than 80 exons, produces a 14 kb mRNA and contains at least 8 independent tissue-specific promoters and 2 poly A sites. The dystrophin mRNA can undergo differential splicing and produce a range of transcripts that encode a large set of proteins. Dystrophin represents approximately 0.002 % of total striated muscle protein and localizes to triadic junctions in skeletal muscle, where it is thought to influence calcium ion homeostasis and force transmission.
- Poids moléculaire
- 427kDa
- ID gène
- 1756
- UniProt
- P11532
- Pathways
- Skeletal Muscle Fiber Development
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