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ERCC1 anticorps (AA 191-281)

ERCC1 Reactivité: Humain IHC, StM Hôte: Souris Monoclonal ERCC1-2318 unconjugated
N° du produit ABIN6939333
  • Antigène Voir toutes ERCC1 Anticorps
    ERCC1 (Excision Repair Cross Complementing Polypeptide-1 (ERCC1))
    Épitope
    • 15
    • 11
    • 10
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 191-281
    Reactivité
    • 86
    • 37
    • 24
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 59
    • 25
    • 2
    Souris
    Clonalité
    • 60
    • 26
    Monoclonal
    Conjugué
    • 52
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ERCC1 est non-conjugé
    Application
    • 74
    • 43
    • 15
    • 13
    • 13
    • 12
    • 12
    • 8
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Staining Methods (StM)
    Specificité
    Recognizes a protein of 110 kDa, identified as Excision Repair Cross Complementing 1 (ERCC1). It is a mammalian nucleotide excision repair (NER) enzyme involved in repair of damaged DNA. ERCC1 is a homologous to RAD10 in Saccharomyces cerevisiae, which is required in mitotic intrachromosomal recombination and repair. ERCC1 is required in repair of cisplatin-induced DNA adducts and ultraviolet (UV)-induced DNA damage. High expression of ERCC1 has been linked to tumor progression in a variety of cancers including non-small cell lung cancer (NSCLC), squamous cell carcinoma of the head, ovarian cancer and esophageal cancer.
    Purification
    Purified by Protein A/G
    Immunogène
    Recombinant fragment (around aa 191-281) of human ERCC1 protein (exact sequence is proprietary)
    Clone
    ERCC1-2318
    Isotype
    IgG2b kappa
    Top Product
    Discover our top product ERCC1 Anticorps primaire
  • Indications d'application

    Positive Control: HeLa, HepG2 cells. Tonsil or Prostate.

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-80 °C
    Stockage commentaire
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Date de péremption
    24 months
  • Antigène
    ERCC1 (Excision Repair Cross Complementing Polypeptide-1 (ERCC1))
    Autre désignation
    ERCC1 (ERCC1 Produits)
    Synonymes
    anticorps COFS4, anticorps RAD10, anticorps UV20, anticorps Ercc-1, anticorps ercc1, anticorps T12H1.18, anticorps T12H1_18, anticorps UV REPAIR DEFICIENT 7, anticorps UVR7, anticorps ERCC excision repair 1, endonuclease non-catalytic subunit, anticorps excision repair cross-complementing rodent repair deficiency, complementation group 1, anticorps DNA excision repair protein ERCC-1, anticorps nucleotide repair protein, anticorps excision repair cross-complementation group 1 L homeolog, anticorps excision repair cross-complementation group 1, anticorps ERCC1, anticorps Ercc1, anticorps CC1G_04546, anticorps CpipJ_CPIJ013903, anticorps PITG_13719, anticorps ercc1, anticorps ercc1.L
    Poids moléculaire
    110kDa
    ID gène
    2067
    UniProt
    P07992
    Pathways
    Réparation de l'ADN, Production of Molecular Mediator of Immune Response
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