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FAT Atypical Cadherin 2 (FAT2) anticorps

FAT2 Reactivité: Humain IF, FACS, IHC, StM Hôte: Souris Monoclonal 8C5 unconjugated
N° du produit ABIN6939371
  • Antigène Voir toutes FAT Atypical Cadherin 2 (FAT2) Anticorps
    FAT Atypical Cadherin 2 (FAT2)
    Reactivité
    • 14
    • 1
    • 1
    Humain
    Hôte
    • 9
    • 5
    Souris
    Clonalité
    • 9
    • 5
    Monoclonal
    Conjugué
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Inconjugué
    Application
    • 10
    • 9
    • 9
    • 3
    • 1
    • 1
    • 1
    Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (IHC), Staining Methods (StM)
    Specificité
    Recognizes a protein of 480 kDa, which is identified as FAT2. The cadherins represent a family of Ca2+-dependent adhesion molecules that function to mediate cell-to-cell binding that is critical for the maintenance of structure and morphogenesis. Cadherins each contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short C-terminal intracellular domain interacts with a variety of cytoplasmic proteins, including -catenin, to regulate cadherin function. The cadherin superfamily includes cadherins, protocadherins, desmogleins and desmocollins. FAT2 (FAT tumor suppressor homolog 2) is a single-pass type I membrane protein that belongs to the protocadherin subfamily of cadherins. FAT2 contains one Laminin G-like domain, two EGF-like domains and 32 cadherin domains and is believed to function as a cell adhesion molecule, controlling cell proliferation and playing an important role in cerebellum development.
    Purification
    Purified by Protein A/G
    Immunogène
    Purified recombinant human FAT2 fusion protein.
    Clone
    8C5
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product FAT2 Anticorps primaire
  • Indications d'application

    Positive Control: Esophagus, Cervix, Uterus, Tonsil or Cerebellum.

    Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-80 °C
    Stockage commentaire
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Date de péremption
    24 months
  • Antigène
    FAT Atypical Cadherin 2 (FAT2)
    Autre désignation
    FAT2 (FAT2 Produits)
    Synonymes
    anticorps EMI2, anticorps Fath2, anticorps Gm523, anticorps mKIAA0811, anticorps CDHF8, anticorps CDHR9, anticorps HFAT2, anticorps MEGF1, anticorps FAT atypical cadherin 2, anticorps Fat2, anticorps FAT2
    Poids moléculaire
    480kDa
    ID gène
    2196
    UniProt
    Q9NYQ8
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