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FcRn anticorps (AA 24-215)

FcRn Reactivité: Humain IHC, ISt, StM Hôte: Souris Monoclonal FCGRT-2932 unconjugated
N° du produit ABIN6939380
  • Antigène Voir toutes FcRn Anticorps
    FcRn (IgG receptor FcRn (FcRn))
    Épitope
    • 14
    • 10
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 24-215
    Reactivité
    • 42
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 39
    • 8
    • 1
    Souris
    Clonalité
    • 40
    • 8
    Monoclonal
    Conjugué
    • 23
    • 5
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp FcRn est non-conjugé
    Application
    • 30
    • 28
    • 7
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), Immunostaining (ISt), Staining Methods (StM)
    Purification
    Purified by Protein A/G
    Immunogène
    Recombinant fragment of human FCGRT protein (around aa 24-215) (Exact sequence is proprietary)
    Clone
    FCGRT-2932
    Isotype
    IgG2b kappa
    Top Product
    Discover our top product FcRn Anticorps primaire
  • Indications d'application

    Positive Control: THP1 or HepG2 cells. Cerebellum or Testis.

    Known Application: Immunohistochemistry (Formalin-fixed) (2-4 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-80 °C
    Stockage commentaire
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Date de péremption
    24 months
  • Antigène
    FcRn (IgG receptor FcRn (FcRn))
    Autre désignation
    FCGRT (FcRn Produits)
    Synonymes
    anticorps FCRN, anticorps alpha-chain, anticorps FcRn, anticorps Fc fragment of IgG receptor and transporter, anticorps Fc receptor, IgG, alpha chain transporter, anticorps FCGRT, anticorps Fcgrt
    Sujet
    This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. FCGRT is present in the intestinal epithelium of neonates and mediates the selective uptake of immunoglobulin G (IgG) in mothers' milk, thereby helping newborn to acquire passive immunity. FCGRT is comprised of a heavy chain and -2-Microglobulin. FCGRT localizes in endosomes of vascular endothelial cells and selectively recycles IgG to the cell surface, thus protecting IgG from lysosomal degradation.
    Poids moléculaire
    46kDa
    ID gène
    2217
    UniProt
    P55899
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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