FcRn anticorps (AA 24-215)
-
- Antigène Voir toutes FcRn Anticorps
- FcRn (IgG receptor FcRn (FcRn))
-
Épitope
- AA 24-215
-
Reactivité
- Humain
-
Hôte
- Souris
-
Clonalité
- Monoclonal
-
Conjugué
- Cet anticorp FcRn est non-conjugé
-
Application
- Immunohistochemistry (IHC), Immunostaining (ISt), Staining Methods (StM)
- Purification
- Purified by Protein A/G
- Immunogène
- Recombinant fragment of human FCGRT protein (around aa 24-215) (Exact sequence is proprietary)
- Clone
- FCGRT-2932
- Isotype
- IgG2b kappa
- Top Product
- Discover our top product FcRn Anticorps primaire
-
-
- Indications d'application
-
Positive Control: THP1 or HepG2 cells. Cerebellum or Testis.
Known Application: Immunohistochemistry (Formalin-fixed) (2-4 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- Restrictions
- For Research Use only
-
- Concentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-80 °C
- Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Date de péremption
- 24 months
-
- Antigène
- FcRn (IgG receptor FcRn (FcRn))
- Autre désignation
- FCGRT (FcRn Produits)
- Synonymes
- anticorps FCRN, anticorps alpha-chain, anticorps FcRn, anticorps Fc fragment of IgG receptor and transporter, anticorps Fc receptor, IgG, alpha chain transporter, anticorps FCGRT, anticorps Fcgrt
- Sujet
- This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. FCGRT is present in the intestinal epithelium of neonates and mediates the selective uptake of immunoglobulin G (IgG) in mothers' milk, thereby helping newborn to acquire passive immunity. FCGRT is comprised of a heavy chain and -2-Microglobulin. FCGRT localizes in endosomes of vascular endothelial cells and selectively recycles IgG to the cell surface, thus protecting IgG from lysosomal degradation.
- Poids moléculaire
- 46kDa
- ID gène
- 2217
- UniProt
- P55899
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
-