Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

ICOSLG anticorps (AA 23-149)

ICOSLG Reactivité: Humain ELISA, IHC, Coat, StM, ISt Hôte: Souris Monoclonal ICOSL-3260 unconjugated
N° du produit ABIN6939408
  • Antigène Voir toutes ICOSLG Anticorps
    ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))
    Épitope
    • 7
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 23-149
    Reactivité
    • 67
    • 16
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 42
    • 27
    • 8
    • 1
    Souris
    Clonalité
    • 40
    • 37
    • 1
    Monoclonal
    Conjugué
    • 50
    • 8
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ICOSLG est non-conjugé
    Application
    • 41
    • 32
    • 30
    • 14
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC), Coating (Coat), Staining Methods (StM), Immunostaining (ISt)
    Specificité
    This MAb recognizes a protein of 36 kDa, identified as ICOS-L. It is a ligand for the ICOS receptor that initiates T and B cell proliferation and cytokine secretion. ICOS-L interactions play an essential role in T cell-dependent B cell activation in peripheral lymphoid organs such as spleen and lymph nodes. ICOS-L protein is present in myeloid leukocytes, and by Northern blot there are 2.4, 3.0, and 7.0 kb transcripts in brain, heart, kidney, and liver, with lower expression in colon and thymus, and a 1.1 kb transcript in leukocytes. Tumor necrosis factor alpha (TNF), granulocyte-macrophage colony-stimulating factor (GM-CSF) and interleukin-4 (IL-4) enhance its expression. LPS-induced up-regulation of ICOS-L is dependent on the MyD88-dependent signaling pathway.
    Purification
    Purified by Protein A/G
    Immunogène
    Recombinant fragment of human ICOSLG (B7RP-1) protein (around aa 23-149) (exact sequence is proprietary)
    Clone
    ICOSL-3260
    Isotype
    IgG2b kappa
    Top Product
    Discover our top product ICOSLG Anticorps primaire
  • Indications d'application

    Positive Control: HL60, HuT78 and HUVEC cells. Prostate or Colon Carcinoma.

    Known Application: ELISA (For coating, order antibody without BSA),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with0.05 % BSA & 0.05 % azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-80 °C
    Stockage commentaire
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Date de péremption
    24 months
  • Antigène
    ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))
    Autre désignation
    ICOSLG (ICOSLG Produits)
    Poids moléculaire
    36kDa
    ID gène
    23308
    UniProt
    O75144
    Pathways
    Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
Vous êtes ici:
Support technique