Recombinant FTL anticorps (AA 38-165)

N° du produit ABIN6939462

Détail du produit anti-FTL anticorps

Antigène: FTL (Ferritin, Light Polypeptide (FTL))

Type d'anticorp: Recombinant Antibody

Épitope: AA 38-165

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FTL est non-conjugé

Application: Immunohistochemistry (IHC), Staining Methods (StM)

Purification: Purified by Protein A/G

Immunogène: Recombinant fragment (around aa 38-165) of human FTL protein (exact sequence is proprietary)

Clone: RFTL-1388

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Positive Control: HepG2, HeLa, HL-60 or 293T cells. Pancreas, Liver, Cerebellum or Testis.

Known Application: Immunohistochemistry (Formalin-fixed) (0.1-0.2 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur FTL

Antigène: FTL (Ferritin, Light Polypeptide (FTL))

Autre désignation: FTL (FTL Produits)

Synonymes: anticorps NBIA3, anticorps apoferritin, anticorps ferritin, anticorps fhc, anticorps fth, anticorps fth1, anticorps fthl6, anticorps ftn-2, anticorps pig15, anticorps plif, anticorps FT, anticorps Ftl, anticorps Ftl-1, anticorps L-ferritin, anticorps FTL, anticorps Ftl1, anticorps FTL2, anticorps FTD, anticorps ferritin light chain, anticorps ferritin, heavy polypeptide 1 L homeolog, anticorps ferritin light polypeptide 1, anticorps ferritin, light polypeptide, anticorps ferritin light-chain, anticorps ferritin light chain 1, anticorps FTL, anticorps fth1.L, anticorps Ftl1, anticorps CpipJ_CPIJ004069, anticorps Ftl

Sujet: Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.

Poids moléculaire: 19-25kDa

ID gène: 2512

UniProt: P02792

Pathways: Transition Metal Ion Homeostasis