Gastrin anticorps

N° du produit ABIN6939464

Détail du produit anti-Gastrin anticorps

Antigène: Gastrin (GAST)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Gastrin est non-conjugé

Application: ELISA, Coating (Coat)

Purification: Purified by Protein A/G

Immunogène: Recombinant full-length human GAST protein

Clone: GAST-2631

Isotype: IgG2c kappa

Information d'application

Indications d'application:

Positive Control: Human Pituitary or Stomach.

Known Application: ELISA (For coating use Ab at 1-5 μg/mL, order Ab without BSA) Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur Gastrin

Antigène: Gastrin (GAST)

Autre désignation: GAST (GAST Produits)

Synonymes: anticorps GAS, anticorps Gas, anticorps PPG34, anticorps GAST, anticorps gastrin, anticorps GAST, anticorps Gast

Sujet: Gastrin, is a hormone that normally formed by mucosal cells in the gastric antrum and by the D cells of the pancreatic islets. Its primary function is to stimulate secretion of HCl by the gastric mucosa. HCl, in turn, inhibits gastrin formation. It also responsible for stimulating smooth muscle contraction and increasing blood circulation and water secretion in the stomach and intestine. Gastrin is regulated by epidermal growth factor in both mice and humans. Gastrin is excreted in excess by pancreatic tumors in the Zollinger-Ellison syndrome. Gastrin-Releasing Peptide (GRP) stimulates the release of gastrin as well as other gastrointestinal hormones and also acts as an autocrine growth factor for certain cell types. High levels of GRP are found in the human lung just after birth and levels decrease thereafter in parallel with the observed disease in a number of pulmonary neuroendocrine cells. GRP is known to promote lung tumorigenesis in model systems.

Poids moléculaire: 2/4/14kDa

ID gène: 2520

UniProt: P01350