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GP2 anticorps (AA 35-179)

GP2 Reactivité: Humain IHC, ELISA, Coat, StM Hôte: Souris Monoclonal GP2-1712 unconjugated
N° du produit ABIN6939542
  • Antigène Tous les produits GP2
    GP2 (Glycoprotein 2 (Zymogen Granule Membrane) (GP2))
    Épitope
    • 27
    • 8
    • 7
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 35-179
    Reactivité
    • 47
    • 8
    • 4
    • 2
    • 2
    • 1
    Humain
    Hôte
    • 32
    • 24
    Souris
    Clonalité
    • 28
    • 28
    Monoclonal
    Conjugué
    • 28
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp GP2 est non-conjugé
    Application
    • 33
    • 31
    • 23
    • 19
    • 19
    • 12
    • 9
    • 7
    • 3
    • 3
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC), ELISA, Coating (Coat), Staining Methods (StM)
    Aucune reactivité croisée
    Souris
    Purification
    Purified by Protein A/G
    Immunogène
    Recombinant fragment of human GP2 protein (around aa 35-179) (exact sequence is proprietary)
    Clone
    GP2-1712
    Isotype
    IgG2b kappa
  • Indications d'application

    Positive Control: PANC-1 cells. Pancreas.

    Known Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-80 °C
    Stockage commentaire
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Date de péremption
    24 months
  • Antigène
    GP2 (Glycoprotein 2 (Zymogen Granule Membrane) (GP2))
    Autre désignation
    GP2 (GP2 Produits)
    Synonymes
    anticorps ZAP75, anticorps 2310037I18Rik, anticorps AV060639, anticorps gp80, anticorps glycoprotein 2, anticorps glycoprotein 2 (zymogen granule membrane), anticorps GP2, anticorps Gp2
    Classe de substances
    Viral Protein
    Sujet
    GP2 (glycoprotein 2), also known as ZAP75, is a 537 amino acid secreted protein. It is an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. GP2 is cleaved and then released into the pancreatic duct along with exocrine secretions. GP2 binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). GP2 is also expressed on the apical plasma membrane of specialized microfold (M) cells among enterocytes and serves as a transcytotic receptor for mucosal antigens. M cells are considered a promising target for oral vaccination against various infectious diseases.
    Poids moléculaire
    59kDa
    ID gène
    2813
    UniProt
    P55259
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