LGALS13 anticorps (AA 23-134)

N° du produit ABIN6939563

Détail du produit anti-LGALS13 anticorps

Antigène: LGALS13 (Lectin, Galactoside-Binding, Soluble, 13 (LGALS13))

Épitope: AA 23-134

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LGALS13 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Coating (Coat), Staining Methods (StM)

Specificité: It recognizes a 32 kDa protein, which is identified as homodimer of galectin-13 (also known as PP13). Galectins are a family of soluble -galactoside-binding lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. One such member, galectin-13, is a 139 amino acid protein that contains one galectin domain. Possessing lysophospholipase activity, galectin-13 exists as a disulfide-linked homodimer. Galectin-13 is suggested to have a developmental role in the placenta and may display immunobiological activity in feto-maternal blood-spaces. Screening for galectin-13 in maternal serum during the first trimester of pregnancy may serve as a diagnostic marker to predict preterm pre-eclampsia.

Purification: Purified by Protein A/G

Immunogène: Recombinant human Galectin-13 protein fragment (aa23-134)

Clone: PP13-1162

Isotype: IgG2b kappa

Information d'application

Indications d'application:

Positive Control: K-562 cells. Placenta or Spleen.

Known Application: ELISA (For coating, order Ab without BSA),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0 or 10 mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur LGALS13

Antigène: LGALS13 (Lectin, Galactoside-Binding, Soluble, 13 (LGALS13))

Autre désignation: LGALS13 (LGALS13 Produits)

Synonymes: anticorps GAL13, anticorps PLAC8, anticorps PP13, anticorps Gal-11, anticorps Gal-13, anticorps Gal11, anticorps gal-13, anticorps galectin 13, anticorps avian beta-defensin 13, anticorps LGALS13, anticorps AvBD13

Poids moléculaire: 16kDa (monomer), 32kDa (homodimer)

ID gène: 29124

UniProt: Q9UHV8