CD235a/GYPA anticorps

N° du produit ABIN6939585

Détail du produit anti-CD235a/GYPA anticorps

Antigène: CD235a/GYPA (GYPA) (Glycophorin A (GYPA))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD235a/GYPA est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), Staining Methods (StM)

Specificité: Recognizes a sialoglycoprotein of 39 kDa, identified as glycophorin A (GPA). It is present on red blood cells (RBC) and erythroid precursor cells. It has been shown that glycophorin acts as the receptor for Sandei virus and parvovirus. Glycophorins A (GPA) and B (GPB), which are single, trans-membrane sialoglycoproteins. GPA is the carrier of blood group M and N specificities, while GPB accounts for S and U specificities. GPA and GPB provide the cells with a large mucin like surface and it has been suggested this provides a barrier to cell fusion, so minimizing aggregation between red blood cells in the circulation.

Purification: Purified by Protein A/G

Immunogène: Formalin fixed membrane from a Hairy cell leukemia

Clone: JC159

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Positive Control: Erythrocytes in any human tissues.

Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), ,Immunohistochemistry (Formalin-fixed) (0.25-0.5 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur CD235a/GYPA

Antigène: CD235a/GYPA (GYPA) (Glycophorin A (GYPA))

Autre désignation: GYPA (GYPA Produits)

Synonymes: anticorps GYPA, anticorps gpa, anticorps AI853584, anticorps CD235a, anticorps GPA, anticorps GPErik, anticorps GPSAT, anticorps HGpMiV, anticorps HGpMiXI, anticorps HGpSta(C), anticorps MN, anticorps MNS, anticorps PAS-2, anticorps glycophorin A (MNS blood group), anticorps glycophorin A, anticorps GYPA, anticorps Gypa

Poids moléculaire: 39kDa

ID gène: 2993, 2994

UniProt: P02724

Pathways: Maintenance of Protein Location