HLA-ABC anticorps
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- Antigène Voir toutes HLA-ABC Anticorps
- HLA-ABC
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Reactivité
- Humain, Souris, Non-Human Primate
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp HLA-ABC est non-conjugé
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Application
- Flow Cytometry (FACS), Immunofluorescence (IF)
- Specificité
- Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.
- Purification
- Purified by Protein A/G
- Immunogène
- Human peripheral blood leukocytes
- Clone
- 246-B8-E7
- Isotype
- IgG2a kappa
- Top Product
- Discover our top product HLA-ABC Anticorps primaire
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- Indications d'application
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Positive Control: THP-1 and Jurkat cells. Tonsil or lymph node.
Known Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.
- Restrictions
- For Research Use only
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- Concentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-80 °C
- Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Date de péremption
- 24 months
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- Antigène
- HLA-ABC
- Autre désignation
- HLA-A, HLA-B, HLA-C (HLA-ABC Produits)
- Synonymes
- anticorps HLAA, anticorps major histocompatibility complex, class I, A, anticorps HLA-A
- Poids moléculaire
- ~41kDa
- ID gène
- 3105, 3106, 3107
- UniProt
- P01889, P30443, P30499
- Pathways
- TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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