IFNA1 anticorps

N° du produit ABIN6939689

Détail du produit anti-IFNA1 anticorps

Antigène: IFNA1 (Interferon, alpha 1 (IFNA1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IFNA1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Purification: Purified by Protein A/G

Immunogène: Purified recombinant human IFN-alpha1

Clone: Feb-48

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Positive Control: Stimulated human peripheral blood mononuclear cells.

Known Application: Flow Cytometry (0.5-1 μg/million cells), Western Blot (1-2 μg/mL), Immunohistochemistry (frozen), Immunofluorescence (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur IFNA1

Antigène: IFNA1 (Interferon, alpha 1 (IFNA1))

Autre désignation: IFNA1 (IFNA1 Produits)

Synonymes: anticorps IFL, anticorps IFN, anticorps IFN-ALPHA, anticorps IFN-alphaD, anticorps IFNA13, anticorps IFNA@, anticorps Ifa1, anticorps IFN-ALPHA-1, anticorps IFN1@, anticorps IFNA1, anticorps IFN-alpha, anticorps IFN-gamma, anticorps IFNA, anticorps IFNA2, anticorps IFNA6, anticorps IFN-alpha1, anticorps interferon alpha 13, anticorps interferon alpha 1, anticorps interferon, alpha 1, anticorps interferon, alpha 13, anticorps interferon, anticorps interferon-alpha 1, anticorps interferon, alpha, leukocyte, anticorps interferon-alpha-14, anticorps IFNA13, anticorps IFNA1, anticorps Ifna1, anticorps ifna1, anticorps IFNA3, anticorps IFN-ALPHA-14

Sujet: This MAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.

Poids moléculaire: 16-27kDa

ID gène: 3439

UniProt: P01562

Pathways: Signalistation JAK/STAT, Hepatitis C