IFNA2 anticorps

N° du produit ABIN6939691

Détail du produit anti-IFNA2 anticorps

Antigène: IFNA2 (Interferon, alpha 2 (IFNA2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IFNA2 est non-conjugé

Application: ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Coating (Coat), Blocking Peptide (BP), Activity Assay (AcA)

Specificité: Recognizes a protein of 16-27 kDa, identified as human interferon-II) (IFN-(II). Its epitope maps between aa112-148 of IFN-II) (total aa172). This MAb is specific for IFN-(II) and does not cross-react with IFN-(I). The site recognized by this MAb is called site I and is responsible for the antiviral and anti-proliferative activities of IFN-(II). Epitopes of N27 and N39 MAbs are different and represent a good combination of antibodies to set up an ELISA assay for the quantitation of IFN-(II) after viral infections. The IFN- family consists of 24 or more genes or pseudo-genes. IFN-II) is one of the two distinct families (I and II) of human IFN-. The -interferon are mainly produced by lymphocytes, monocytes, macrophages, and cell lines such as Namalwa and KG1 following induction by viruses, nucleic acids, and glucocorticoid hormones. They are involved in virus resistance on target cells, inhibition of cell proliferation, induction of cytokines and regulation of expression of MHC class I antigens.

Purification: Purified by Protein A/G

Immunogène: Purified recombinant human IFN-alpha2

Clone: N27

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Positive Control: Stimulated human peripheral blood mononuclear cells.

Known Application: ELISA (For coating, order Ab without BSA), Blocking Activity (Order Ab without Azide), Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur IFNA2

Antigène: IFNA2 (Interferon, alpha 2 (IFNA2))

Autre désignation: IFNA2 (IFNA2 Produits)

Synonymes: anticorps IFN-alphaA, anticorps IFNA, anticorps IFNA2B, anticorps INFA2, anticorps Ifa2, anticorps IFNA2, anticorps interferon alpha 2, anticorps interferon, alpha 2, anticorps interferon-alpha-2, anticorps interferon alpha-2, anticorps IFNA2, anticorps Ifna2, anticorps ifna2, anticorps IFN-ALPHA2, anticorps LOC102142148

Poids moléculaire: 16-27kDa

ID gène: 3440

UniProt: P01563

Pathways: Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Hepatitis C