CD103 anticorps
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- Antigène Voir toutes CD103 (ITGAE) Anticorps
- CD103 (ITGAE) (Integrin, alpha E (Antigen CD103, Human Mucosal Lymphocyte Antigen 1, alpha Polypeptide) (ITGAE))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD103 est non-conjugé
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Application
- Immunohistochemistry (IHC), Staining Methods (StM)
- Specificité
- This MAb recognizes a protein of 150 kDa, identified as CD103, which is the alpha-E integrin subunit of the heterodimeric alpha-E beta-7 (aEb7) integrin belonging to a small beta-7 integrin subfamily. CD103 is expressed on more than 95 % of intraepithelial CD8+ cells and on 40 % of mucosa-associated T cells, whereas less than 2 % of resting blood lymphocytes are CD103-positive. In several malignant conditions, such as T-cell lymphomas and hairy cell leukemia (HCL), the cells express CD103. Antibody to CD103 is an extremely useful addition to the IHC panel for the diagnosis of hairy cell leukemia (HCL).
- Purification
- Purified by Protein A/G
- Immunogène
- Recombinant human ITGAE protein fragment (exact sequence is proprietary)
- Clone
- ITGAE-2063
- Isotype
- IgG2c kappa
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- Indications d'application
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Positive Control: Tonsil, Colon or Stomach.
Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
- Restrictions
- For Research Use only
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- Concentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-80 °C
- Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Date de péremption
- 24 months
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- Antigène
- CD103 (ITGAE) (Integrin, alpha E (Antigen CD103, Human Mucosal Lymphocyte Antigen 1, alpha Polypeptide) (ITGAE))
- Autre désignation
- ITGAE (ITGAE Produits)
- Synonymes
- anticorps A530055J10, anticorps CD103, anticorps aM290, anticorps alpha-E1, anticorps alpha-M290, anticorps HUMINAE, anticorps integrin alpha E, epithelial-associated, anticorps integrin subunit alpha E, anticorps Itgae, anticorps ITGAE
- Poids moléculaire
- 150kDa
- ID gène
- 3682
- UniProt
- P38570
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