Recombinant KRT6A anticorps

N° du produit ABIN6939868

Détail du produit anti-KRT6A anticorps

Antigène: KRT6A (Keratin 6A (KRT6A))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp KRT6A est non-conjugé

Application: Immunohistochemistry (IHC), Staining Methods (StM)

Specificité: This MAb recognizes a protein of 56 kDa, identified as cytokeratin 6A (KRT6A). In humans, multiple isoforms of Cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns. Cytokeratin 6A is the dominant form in epithelial tissue. Cytokeratin 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyper-proliferation-related keratins). Cytokeratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyper-proliferative situations. Epidermal injury results in activation of keratinocytes, which express KRT6 and KRT16. KRT6 is strongly expressed in about 75 % of head and neck squamous cell carcinomas.

Purification: Purified by Protein A/G

Immunogène: Recombinant full-length human Cytokeratin 6A (KRT6A) protein

Clone: RKRT6A-2100

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Positive Control: Tonsil or basal cell carcinoma.

Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur KRT6A

Antigène: KRT6A (Keratin 6A (KRT6A))

Autre désignation: KRT6A (KRT6A Produits)

Synonymes: anticorps CK6A, anticorps CK6C, anticorps CK6D, anticorps K6A, anticorps K6C, anticorps K6D, anticorps KRT6C, anticorps KRT6D, anticorps 2310016L08Rik, anticorps Krt2-6a, anticorps Krt2-6c, anticorps MK6a, anticorps mK6[a], anticorps CK-6A, anticorps Krt6a, anticorps KRT6A, anticorps keratin 6A, anticorps similar to keratin complex 2, basic, gene 6a, anticorps keratin, type II cytoskeletal 6A, anticorps KRT6A, anticorps Krt6a, anticorps LOC683313, anticorps LOC101112304

Poids moléculaire: 58kDa

ID gène: 3853

UniProt: P02538