KRT14 anticorps (AA 351-472)

N° du produit ABIN6939908

Détail du produit anti-KRT14 anticorps

Antigène: KRT14 (Keratin 14 (KRT14))

Épitope: AA 351-472

Reactivité: Humain, Rat, Souris, Porc

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp KRT14 est non-conjugé

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS), Staining Methods (StM)

Purification: Purified by Protein A/G

Immunogène: Recombinant human KRT14 fragment (around aa351-472) (exact sequence is proprietary)

Clone: KRT14-2375

Isotype: IgG2a kappa

Information d'application

Indications d'application:

Positive Control: A431 or HeLa cells. Skin or Squamous Cell Carcinoma.

Known Application: Flow Cytometry (1-2 μg/million cells), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur KRT14

Antigène: KRT14 (Keratin 14 (KRT14))

Autre désignation: KRT14 (KRT14 Produits)

Synonymes: anticorps CK14, anticorps EBS3, anticorps EBS4, anticorps K14, anticorps NFJ, anticorps AI626930, anticorps Krt-1.14, anticorps Krt1-14, anticorps Ka14, anticorps ouro2, anticorps keratin 14, anticorps keratin 14, type I L homeolog, anticorps KRT14, anticorps Krt14, anticorps krt14.L

Sujet: Cytokeratin 14 (CK14) belongs to the type I (or A or acidic) subfamily of low molecular weight keratins and exists in combination with keratin 5 (type II or B or basic). CK14 is found in basal cells of squamous epithelia, some glandular epithelia, myoepithelium, and mesothelial cells. Anti-CK14 is useful in differentiating squamous cell carcinomas from poorly differentiated epithelial tumors. Anti-CK14 is one of the specific basal markers for distinguishing between basal and non-basal subtypes of breast carcinomas. Anti-CK14 is also a good marker for differentiation of intraductal from invasive salivary duct carcinoma by the positive staining of basal cells surrounding the in-situ neoplasm as well as for differentiation of benign prostate from prostate carcinoma. Furthermore, this antibody has been useful in separating oncocytic tumors of the kidney from its renal mimics, and in identifying metaplastic carcinomas of the breast.

Poids moléculaire: 50kDa

ID gène: 3861

UniProt: P02533