LGALS1/Galectin 1 anticorps (AA 12-108)

N° du produit ABIN6939958

Détail du produit anti-LGALS1/Galectin 1 anticorps

Antigène: LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))

Épitope: AA 12-108

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LGALS1/Galectin 1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Coating (Coat), Staining Methods (StM)

Purification: Purified by Protein A/G

Immunogène: Recombinant fragment (around aa12-108) of human Galectin-1 protein (exact sequence is proprietary)

Clone: GAL1-1831

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Positive Control: HeLa, K562 or 293 cells. Prostate, Kidney, Placenta, Stomach, Skin, Spleen, Brain or Heart.

Known Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur LGALS1/Galectin 1

Antigène: LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))

Autre désignation: LGALS1 (LGALS1 Produits)

Synonymes: anticorps GAL1, anticorps GBP, anticorps Galectin-1, anticorps LGAS1, anticorps LGALS1, anticorps MGC64502, anticorps GB10026, anticorps AA410090, anticorps Gal-1, anticorps Galbp, anticorps L-14.5, anticorps L14, anticorps Lect14, anticorps galectin-1, anticorps Galaptin, anticorps galectin 1, anticorps galectin-1, anticorps lectin, galactoside-binding, soluble, 1 L homeolog, anticorps protein enabled, anticorps lectin, galactose binding, soluble 1, anticorps LGALS1, anticorps Lgals1, anticorps CC1G_05003, anticorps CC1G_05004, anticorps lgals1.L, anticorps LOC408848

Sujet: Galectin-1 is a member of the beta-galactoside-binding family and is a dimeric protein of 14kD participating in a variety of normal and pathological processes, including cancer progression. Galectin-1 can affect the proliferation of normal and malignant cells. Inhibition of cell growth is observed in a lactose-dependent manner as lower concentrations of the lectin stimulate cell proliferation. Galectin-1 may also be implicated in the induction of apoptosis of activated T cells through the binding of exogenous galectin-1 to CD45 Molecules present on the surface of lymphocytes. Galectin-1, reported to be present either at the surface of cancer cells or accumulated around these cells could act as an immunological shield to protect against a T cell immune response and provide an advantage for survival.

Poids moléculaire: 14kDa

ID gène: 3956

UniProt: P09382

Pathways: Carbohydrate Homeostasis