LHCGR anticorps (AA 70-410)
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- Antigène Voir toutes LHCGR Anticorps
- LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))
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Épitope
- AA 70-410
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp LHCGR est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
- Specificité
- Recognizes a protein of 78-85 kDa, which is identified as Luteinizing hormone / choriogonadotropin receptor. Luteinizing hormone plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Choriogonadotropin production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone / choriogonadotropin receptor (LHCGR) as a seven transmembrane, G protein-coupled receptor glycoprotein. LHCGR influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of LHCGR on breast carcinoma correlates in part to the degree of tumor differentiation. LHCGR -positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women.
- Purification
- Purified by Protein A/G
- Immunogène
- Recombinant fragment (around aa 70-410) of human LHCGR protein (exact sequence is proprietary)
- Clone
- LHCGR-1416
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product LHCGR Anticorps primaire
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- Indications d'application
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Positive Control: HepG2 or Jurkat cells. Ovary or Testis.
Known Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.
- Restrictions
- For Research Use only
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- Concentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-80 °C
- Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Date de péremption
- 24 months
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- Antigène
- LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))
- Autre désignation
- LHCGR (LHCGR Produits)
- Synonymes
- anticorps HHG, anticorps LCGR, anticorps LGR2, anticorps LH/CG-R, anticorps LH/CGR, anticorps LHR, anticorps LHRHR, anticorps LSH-R, anticorps ULG5, anticorps Gpcr19-rs1, anticorps LH-R, anticorps Lhr, anticorps LSHR, anticorps lhr, anticorps GTHR-II, anticorps zfGTHR-II, anticorps LHCGR, anticorps LOC100222883, anticorps lh-r, anticorps LOC100305044, anticorps luteinizing hormone/choriogonadotropin receptor, anticorps luteinizing hormone/choriogonadotropin receptor L homeolog, anticorps luteinizing hormone receptor, anticorps LHCGR, anticorps Lhcgr, anticorps lhcgr, anticorps lhcgr.L, anticorps lhr, anticorps LOC100305044
- Poids moléculaire
- 78-85kDa
- ID gène
- 3973
- UniProt
- P22888
- Pathways
- Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, cAMP Metabolic Process, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
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