Moesin anticorps

N° du produit ABIN6940082

Détail du produit anti-Moesin anticorps

Antigène: Moesin (MSN)

Reactivité: Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Moesin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Staining Methods (StM)

Specificité: Recognizes 78 kDa moesin protein. Moesin, a member of the talin-4.1 superfamily, is a linking protein of the sub-membranous actin cytoskeleton. It is expressed in variable amounts in cells of different phenotypes such as macrophages, lymphocytes, fibroblastic, endothelial, epithelial, and neuronal cell lines but not in blood cells. The ERM proteins, ezrin, radixin, and moesin are involved in a variety of cellular functions, such as cell adhesion, migration, and the organization of cell surface structures, and are highly homologous, both in protein sequence and in functional activity, with merlin/schwannomin, a neurofibromatosis-2-associated tumor-suppressor protein. Cell lines of epithelial and mesothelial origin contain both moesin and radixin whereas cells of endothelial and lymphoid origin express moesin.

Purification: Purified by Protein A/G

Immunogène: Recombinant full-length human Moesin protein

Clone: MSN-491

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Positive Control: K562, HT-29, CH3LC or HUVEC cells. Uterus, Placenta, Tonsil, Melanoma, Testicular Carcinoma.

Known Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (2-4 μg/mL), Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur Moesin

Antigène: Moesin (MSN)

Autre désignation: MSN (MSN Produits)

Synonymes: anticorps CG10701, anticorps D17, anticorps Dmel\\CG10701, anticorps Dmoe, anticorps EMR1, anticorps ERM, anticorps Emr1, anticorps anon-WO03040301.155, anticorps anon-WO03040301.157, anticorps anon-WO03040301.159, anticorps anon-WO03040301.161, anticorps dMoe, anticorps gma, anticorps l(1)G0067, anticorps l(1)G0323, anticorps l(1)G0404, anticorps l(1)G0415, anticorps moe, anticorps moesin/ezrin/radixin homolog mRNA, anticorps cb567, anticorps rdx, anticorps wu:fb14b03, anticorps zgc:85640, anticorps MSN, anticorps C78546, anticorps moesin, anticorps Moesin, anticorps moesin a, anticorps moesin L homeolog, anticorps MSN, anticorps Moe, anticorps msna, anticorps msn.L, anticorps moes, anticorps Msn

Poids moléculaire: 78kDa

ID gène: 4478

UniProt: P26038

Pathways: Asymmetric Protein Localization