MUC2 anticorps
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- Antigène Voir toutes MUC2 Anticorps
- MUC2 (Mucin 2, Oligomeric Mucus/gel-Forming (MUC2))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp MUC2 est non-conjugé
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Application
- Immunohistochemistry (IHC), Staining Methods (StM)
- Specificité
- Recognizes a single glycoprotein of 520 kDa, identified as mucin 2 (MUC2). This MAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium.MUC2 is specifically expressed in goblet cells of the small intestine in about 65 % of colonic carcinomas and about 40 % of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary.
- Aucune reactivité croisée
- Rat (Rattus)
- Purification
- Purified by Protein A/G
- Immunogène
- Recombinant fragment covering tandem repeats of human MUC2 protein (exact sequence is proprietary)
- Clone
- MLP-842
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product MUC2 Anticorps primaire
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- Indications d'application
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Positive Control: LS174T cells. Human small intestine (IHC).
Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris-HCl buffer, pH 10.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- Restrictions
- For Research Use only
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- Concentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-80 °C
- Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Date de péremption
- 24 months
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- Antigène
- MUC2 (Mucin 2, Oligomeric Mucus/gel-Forming (MUC2))
- Autre désignation
- MUC2 (MUC2 Produits)
- Poids moléculaire
- 520kDa
- ID gène
- 4583
- UniProt
- Q02817
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