Recombinant MUC2 anticorps

N° du produit ABIN6940119

Détail du produit anti-MUC2 anticorps

Antigène: MUC2 (Mucin 2, Oligomeric Mucus/gel-Forming (MUC2))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MUC2 est non-conjugé

Application: Immunohistochemistry (IHC), Staining Methods (StM), Immunostaining (ISt)

Specificité: Recognizes a single glycoprotein of 520 kDa, identified as mucin 2 (MUC2). This MAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Its epitope has been defined as GTQTP (GlyThrGlnThrPro). Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine in about 65 % of colonic carcinomas and about 40 % of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary.

Purification: Purified by Protein A/G

Immunogène: A synthetic peptide of 29 amino acids, KYPTTTPISTTTMVTPTPTPTGTQTPTTT from MUC2 protein, coupled to KLH.

Clone: RMLP-842

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Positive Control: LS174T cells. Human small intestine (IHC).

Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur MUC2

Antigène: MUC2 (Mucin 2, Oligomeric Mucus/gel-Forming (MUC2))

Autre désignation: MUC2 (MUC2 Produits)

Synonymes: anticorps 2010015E03Rik, anticorps MCM, anticorps wnn, anticorps MLP, anticorps MUC-2, anticorps SMUC, anticorps HH-Muc, anticorps mucin 2, anticorps mucin 2, oligomeric mucus/gel-forming, anticorps mucin-2, anticorps Muc2, anticorps MUC2, anticorps LOC100724045

Poids moléculaire: 520kDa

ID gène: 4583

UniProt: Q02817