Recombinant MUC5AC anticorps

N° du produit ABIN6940127

Détail du produit anti-MUC5AC anticorps

Antigène: MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris, Rat, Singe, Cat, Lapin, Poulet, Porc, Hedgehog

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MUC5AC est non-conjugé

Application: Immunohistochemistry (IHC), Staining Methods (StM)

Specificité: This MAb recognizes the peptide core of gastric mucin M1 (recently identified as Mucin 5AC).Its epitope is located in the C-terminal cysteine rich part of the peptide core of MUC5AC. Its epitope is destroyed by beta-mercaptoethanol but not by periodate treatment. This mucin is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies, Anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification of intestinal metaplasia as well as in the identification of pancreatic carcinoma and pre-cancerous changes vs. normal pancreas.

Aucune reactivité croisée: Boeuf (Vache)

Purification: Purified by Protein A/G

Immunogène: M1 mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le(a-b) patient

Clone: RMUC5AC-3779

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Positive Control: Human colon or stomach (IHC).

Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur MUC5AC

Antigène: MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))

Autre désignation: MUC5AC (MUC5AC Produits)

Synonymes: anticorps MUC5, anticorps TBM, anticorps leB, anticorps 2210005L13Rik, anticorps MGM, anticorps mucin 5AC, oligomeric mucus/gel-forming, anticorps putative gastric mucin, anticorps mucin 5, subtypes A and C, tracheobronchial/gastric, anticorps mucin 2, oligomeric mucus/gel-forming, anticorps MUC5AC, anticorps Smp_144070, anticorps Muc5ac, anticorps MUC2

Poids moléculaire: >1,000kDa

ID gène: 4586

UniProt: P98088