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Recombinant MUC5AC anticorps

MUC5AC Reactivité: Humain, Souris, Rat, Singe, Cat, Lapin, Poulet, Porc, Hedgehog IHC, StM Hôte: Souris Monoclonal rMUC5AC-3779 unconjugated Recombinant Antibody
N° du produit ABIN6940127
  • Antigène Voir toutes MUC5AC Anticorps
    MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))
    Type d'anticorp
    Recombinant Antibody
    Reactivité
    • 92
    • 52
    • 38
    • 18
    • 17
    • 16
    • 14
    • 13
    • 12
    • 6
    • 1
    • 1
    Humain, Souris, Rat, Singe, Cat, Lapin, Poulet, Porc, Hedgehog
    Hôte
    • 60
    • 58
    • 1
    Souris
    Clonalité
    • 61
    • 58
    Monoclonal
    Conjugué
    • 58
    • 16
    • 9
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MUC5AC est non-conjugé
    Application
    • 53
    • 39
    • 30
    • 29
    • 29
    • 19
    • 18
    • 16
    • 15
    • 13
    • 13
    • 12
    • 7
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Staining Methods (StM)
    Specificité
    This MAb recognizes the peptide core of gastric mucin M1 (recently identified as Mucin 5AC).Its epitope is located in the C-terminal cysteine rich part of the peptide core of MUC5AC. Its epitope is destroyed by beta-mercaptoethanol but not by periodate treatment. This mucin is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies, Anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification of intestinal metaplasia as well as in the identification of pancreatic carcinoma and pre-cancerous changes vs. normal pancreas.
    Aucune reactivité croisée
    Boeuf (Vache)
    Purification
    Purified by Protein A/G
    Immunogène
    M1 mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le(a-b) patient
    Clone
    RMUC5AC-3779
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product MUC5AC Anticorps primaire
  • Indications d'application

    Positive Control: Human colon or stomach (IHC).

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-80 °C
    Stockage commentaire
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Date de péremption
    24 months
  • Antigène
    MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))
    Autre désignation
    MUC5AC (MUC5AC Produits)
    Synonymes
    anticorps MUC5, anticorps TBM, anticorps leB, anticorps 2210005L13Rik, anticorps MGM, anticorps mucin 5AC, oligomeric mucus/gel-forming, anticorps putative gastric mucin, anticorps mucin 5, subtypes A and C, tracheobronchial/gastric, anticorps mucin 2, oligomeric mucus/gel-forming, anticorps MUC5AC, anticorps Smp_144070, anticorps Muc5ac, anticorps MUC2
    Poids moléculaire
    >1,000kDa
    ID gène
    4586
    UniProt
    P98088
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