Myogenin anticorps (AA 30-224)
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- Antigène Voir toutes Myogenin (MYOG) Anticorps
- Myogenin (MYOG) (Myogenin (Myogenic Factor 4) (MYOG))
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Épitope
- AA 30-224
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Reactivité
- Humain, Souris, Rat, Porc, Cat
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Myogenin est non-conjugé
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Application
- Immunohistochemistry (IHC), Staining Methods (StM)
- Purification
- Purified by Protein A/G
- Immunogène
- Human myogenin recombinant protein (MGN185), Rat myogenin recombinant fragment containing amino acid 30-224 (F5D)
- Clone
- MGN185-F5D
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product MYOG Anticorps primaire
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- Indications d'application
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Positive Control: Rh-30 cells. Skeletal muscle or rhabdomyosarcoma.
Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- Restrictions
- For Research Use only
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- Concentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-80 °C
- Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Date de péremption
- 24 months
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- Antigène
- Myogenin (MYOG) (Myogenin (Myogenic Factor 4) (MYOG))
- Autre désignation
- MYOG (MYOG Produits)
- Synonymes
- anticorps cb553, anticorps zgc:100763, anticorps LOC446037, anticorps myf4, anticorps Xmyog, anticorps myogenin, anticorps LOC100136471, anticorps LOC100224062, anticorps LOC100303673, anticorps MYF4, anticorps bHLHc3, anticorps myo, anticorps myf-4, anticorps myogenin, anticorps myogenin (myogenic factor 4), anticorps MYOG, anticorps myog, anticorps LOC100303673, anticorps Myog
- Sujet
- Myogenin is a member of the MyoD family of myogenic basic helix-loop-helix (bHLH) transcription factors that also includes MyoD, Myf-5, and MRF4 (also known as herculinor Myf-6). MyoD family members are expressed exclusively in skeletal muscle and play a key role in activating myogenesis by binding to enhancer sequences of muscle-specific genes. The regulatory domain of MyoD is approximately 70 amino acids in length and includes both a basic DNA binding motif and a bHLH dimerization motif.MyoD family members share about 80 % amino acid homology in their bHLH motifs.Anti-myogenin labels the nuclei of myoblasts in developing muscle tissue, and is expressed in tumor cell nuclei of rhabdomyosarcoma and some leiomyosarcomas. Positive nuclear staining may occur in Wilms' tumor.
- Poids moléculaire
- 34kDa
- ID gène
- 4656
- UniProt
- P15173
- Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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