NME2 anticorps

N° du produit ABIN6940215

Détail du produit anti-NME2 anticorps

Antigène: NME2 (Nucleoside diphosphate kinase B (NME2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NME2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Staining Methods (StM)

Purification: Purified by Protein A/G

Immunogène: Recombinant full-length human NME2 protein

Clone: CPTC-NME2-2

Isotype: IgG2a kappa

Information d'application

Indications d'application:

Positive Control: PC3, A549, HeLa, Jurkat cells. Ubiquitously expressed in all tissues.

Known Application: Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur NME2

Antigène: NME2 (Nucleoside diphosphate kinase B (NME2))

Autre désignation: NME2 (NME2 Produits)

Synonymes: anticorps NDKB, anticorps NDPK-B, anticorps NDPKB, anticorps NM23-H2, anticorps NM23B, anticorps PUF, anticorps nm23-2, anticorps p18-12d, anticorps nm23-M2, anticorps NM23-C2, anticorps NME/NM23 nucleoside diphosphate kinase 2, anticorps non-metastatic cells 2, protein (NM23B) expressed in, anticorps NME2, anticorps Nme2

Sujet: The nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells. Based on sequence analysis, nm23 appears highly related to nucleotide diphosphate kinases (NDP). In humans, NDP kinases A and B are identical to two isotypes of human nm23 homologs, namely nm23-H1 and H2, respectively. nm23-H2 is identical in sequence to PuF, a transcription factor that binds to nuclease hypersensitive elements at positions 142 to 115 of the human c-Myc promotor.

Poids moléculaire: 17kDa

ID gène: 4831

UniProt: P22392