Recombinant CD207 anticorps (AA 74-213)

N° du produit ABIN6940245

Détail du produit anti-CD207 anticorps

Antigène: CD207 (CD207 Molecule, Langerin (CD207))

Type d'anticorp: Recombinant Antibody

Épitope: AA 74-213

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD207 est non-conjugé

Application: Western Blotting (WB), ELISA, Coating (Coat)

Purification: Purified by Protein A/G

Immunogène: Recombinant fragment (around aa74-213) of human Langerin protein (exact sequence is proprietary)

Clone: RLGRN-1821

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Positive Control: HeLa or A549 cells (WB).

Known Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur CD207

Antigène: CD207 (CD207 Molecule, Langerin (CD207))

Autre désignation: CD207 (CD207 Produits)

Sujet: Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immuno-stimulatory capacity and play a central role in the initiation and regulation of immune responses. Langerin (CD207) is a Ca2+-dependent, C-type lectin domain containing, type II transmembrane protein that induces epidermal LCs to differentiate into Birbeck granules (BG). BGs are organelles with superimposing and zippering membranes that influence proper class I type antigen presentation to the circulating T cells. Human spleen, lymph node, thymus, liver, lung and heart express Langerin protein.

Poids moléculaire: 48kDa

ID gène: 50489

UniProt: Q9UJ71