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NADPH Oxidase 4 anticorps

NOX4 Reactivité: Humain WB, ELISA, Coat Hôte: Souris Monoclonal NOX4-1245 unconjugated
N° du produit ABIN6940247
  • Antigène Voir toutes NADPH Oxidase 4 (NOX4) Anticorps
    NADPH Oxidase 4 (NOX4)
    Reactivité
    • 97
    • 46
    • 42
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 88
    • 14
    Souris
    Clonalité
    • 80
    • 23
    Monoclonal
    Conjugué
    • 33
    • 10
    • 8
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NADPH Oxidase 4 est non-conjugé
    Application
    • 79
    • 41
    • 40
    • 24
    • 15
    • 14
    • 13
    • 10
    • 9
    • 6
    • 6
    • 3
    • 3
    Western Blotting (WB), ELISA, Coating (Coat)
    Purification
    Purified by Protein A/G
    Immunogène
    Recombinant human NOX4 protein
    Clone
    NOX4-1245
    Isotype
    IgG2b kappa
    Top Product
    Discover our top product NOX4 Anticorps primaire
  • Indications d'application

    Positive Control: PC-12, JAR cells. Kidney.

    Known Application: ELISA (For coating, order Ab without BSA)Western Blot (0.5-1 μg/mL)Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-80 °C
    Stockage commentaire
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Date de péremption
    24 months
  • Antigène
    NADPH Oxidase 4 (NOX4)
    Autre désignation
    NOX4 (NOX4 Produits)
    Synonymes
    anticorps KOX, anticorps KOX-1, anticorps RENOX, anticorps AI648021, anticorps nox4, anticorps NOX4, anticorps NADPH oxidase 4, anticorps NOX4, anticorps Nox4, anticorps nox4, anticorps PTRG_09562
    Sujet
    The superoxide-generating NADPH oxidase includes a membrane-bound flavocytochrome containing two subunits, gp91-phox and p22-phox, and the cytosolic proteins p47-phox and p67-phox. During activation of the NADPH oxidase, p47-phox and p67-phox migrate to the plasma membrane where they associate with the flavocytochrome, cytochrome b558, to form the active enzyme complex. The p22 and gp91-phox subunits also function as surface O2 sensors that initiate cellular signaling in response to hypoxic conditions. NOX4 is a renal gp91-phox homolog highly expressed at the site of erythropoietin production in the proximal convoluted tubule epithelial cells of the renal cortex. It is also expressed in fetal tissues, placenta, glioblastoma and vascular cells.
    Poids moléculaire
    70kDa
    ID gène
    50507
    UniProt
    Q9NPH5
    Pathways
    Carbohydrate Homeostasis, Smooth Muscle Cell Migration
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