PMEPA1 anticorps
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- Antigène Voir toutes PMEPA1 Anticorps
- PMEPA1 (Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp PMEPA1 est non-conjugé
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Application
- Immunohistochemistry (IHC), Staining Methods (StM)
- Purification
- Purified by Protein A/G
- Immunogène
- Recombinant full-length human PMEPA1 protein
- Clone
- PMEPA1-2696
- Isotype
- IgG1 kappa
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- Indications d'application
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Positive Control: Human prostate, breast or renal cell carcinoma tissue (IHC).
Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- Restrictions
- For Research Use only
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- Concentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-80 °C
- Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Date de péremption
- 24 months
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- Antigène
- PMEPA1 (Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1))
- Autre désignation
- PMEPA1 (PMEPA1 Produits)
- Synonymes
- anticorps Tmepai, anticorps PMEPA1, anticorps TMEPAI, anticorps zgc:92731, anticorps tmepai, anticorps STAG1, anticorps 2210418I02Rik, anticorps AW455466, anticorps Erg1.2, anticorps N4wbp4, anticorps Stag1, anticorps prostate transmembrane protein, androgen induced 1, anticorps prostate transmembrane protein, androgen induced 1 L homeolog, anticorps Pmepa1, anticorps PMEPA1, anticorps pmepa1, anticorps pmepa1.L
- Sujet
- PMEPA1 (prostate transmembrane protein, androgen induced 1 is a 287 amino acid single-pass membrane protein that contains WW-binding motifs and localizes to the cell membrane. Expressed at high levels in prostate, kidney and ovary, PMEPA1 interacts with NEDD4 and may play a role in regulating AR (androgen receptor) levels, specifically in prostate cells. Down regulation of PMEPA1 is observed in prostate tumors, suggesting that PMEPA1 may exhibit activity as a tumor suppressor. Overexpression of this protein may play a role in multiple types of cancer.
- Poids moléculaire
- 32kDa
- ID gène
- 56937
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway
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