Recombinant PTGS2 anticorps (AA 442-572)
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- Antigène Voir toutes PTGS2 Anticorps
- PTGS2 (Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2))
- Type d'anticorp
- Recombinant Antibody
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Épitope
- AA 442-572
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp PTGS2 est non-conjugé
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Application
- Immunohistochemistry (IHC), Staining Methods (StM)
- Purification
- Purified by Protein A/G
- Immunogène
- Recombinant human COX2 protein fragment (around aa 442-572) (exact sequence is proprietary)
- Clone
- COX2-3232R
- Isotype
- IgG
- Top Product
- Discover our top product PTGS2 Anticorps primaire
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- Indications d'application
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Positive Control: Human colon or lung carcinoma tissue (IHC).
Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
- Restrictions
- For Research Use only
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- Concentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-80 °C
- Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Date de péremption
- 24 months
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- Antigène
- PTGS2 (Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2))
- Autre désignation
- PTGS2 (PTGS2 Produits)
- Synonymes
- anticorps COX-2, anticorps COX2, anticorps GRIPGHS, anticorps PGG/HS, anticorps PGHS-2, anticorps PHS-2, anticorps hCox-2, anticorps Cox-2, anticorps Pghs2, anticorps TIS10, anticorps Cox2, anticorps cox-2, anticorps CEF147, anticorps PGHS2, anticorps PHSII, anticorps cox2, anticorps gripghs, anticorps pgg/hs, anticorps pghs-2, anticorps phs-2, anticorps PTGS2, anticorps hcox-2, anticorps fj02a10, anticorps ptgs2, anticorps unp1239, anticorps wu:fj02a10, anticorps zCOX-2, anticorps si:dkey-97o5.6, anticorps prostaglandin-endoperoxide synthase 2, anticorps prostaglandin G/H synthase 2, anticorps prostaglandin-endoperoxide synthase 2S homeolog, anticorps prostaglandin-endoperoxide synthase 2a, anticorps prostaglandin-endoperoxide synthase 2b, anticorps PTGS2, anticorps Ptgs2, anticorps LOC100136456, anticorps ptgs2.S, anticorps ptgs2, anticorps ptgs2a, anticorps ptgs2b
- Sujet
- Prostaglandins are a diverse group of autocrine and paracrine hormones that mediate many cellular and physiologic processes. Prostaglandin H2 (PGH2) is an intermediate molecule in formation of the prostaglandins. Cyclooxygenase-1 (Cox-1) and cyclooxygenase-2 (Cox-2) are prostaglandin synthases that catalyze the formation of PGH2 from arachidonic acid (AA). Cox-1 and Cox-2 are isozymes of prostaglandin-endoperoxidase synthase (PTGS). Cox-1 is constitutively expressed in most tissues and is thought to serve in general housekeeping functions. Cox-2 is efficiently induced in migratory cells responding to pro-inflammatory stimuli and is considered to be an important mediator of inflammation. Both enzymes are targets for the nonsteroidal therapeutic anti-inflammatory drugs, NSAIDs. COX2 expression is significantly increased in 85-90 % of human colorectal adenocarcinomas whereas levels of COX-1 are not changed.
- Poids moléculaire
- 70-72kDa
- ID gène
- 5743
- UniProt
- P35354
- Pathways
- Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
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