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BAX anticorps (AA 3-16)

BAX Reactivité: Humain, Singe WB, IHC, IF, FACS, StM Hôte: Souris Monoclonal 2D2 unconjugated
N° du produit ABIN6940472
  • Antigène Voir toutes BAX Anticorps
    BAX (BCL2-Associated X Protein (BAX))
    Épitope
    • 38
    • 32
    • 18
    • 16
    • 15
    • 12
    • 11
    • 10
    • 9
    • 8
    • 8
    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 3-16
    Reactivité
    • 260
    • 158
    • 143
    • 47
    • 32
    • 26
    • 25
    • 18
    • 16
    • 13
    • 9
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Singe
    Hôte
    • 171
    • 97
    • 3
    • 1
    Souris
    Clonalité
    • 185
    • 87
    Monoclonal
    Conjugué
    • 137
    • 16
    • 13
    • 12
    • 10
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp BAX est non-conjugé
    Application
    • 234
    • 114
    • 73
    • 62
    • 52
    • 52
    • 50
    • 40
    • 38
    • 12
    • 12
    • 8
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Staining Methods (StM)
    Specificité
    Recognizes a protein of 21 kDa, identified as the Bax protein. This MAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.
    Aucune reactivité croisée
    Souris, Rat (Rattus)
    Purification
    Purified by Protein A/G
    Immunogène
    A synthetic peptide, aa 3-16 (Cys-GSGEQPRGGGPTSS) of human bax protein.
    Clone
    2D2
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product BAX Anticorps primaire
  • Indications d'application

    Positive Control: Jurkat, K562, HL-60 or HeLa cells. Reed-Sternberg cells in Hodgkin's lymphoma.

    Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (0.5-1 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT) (Staining of formalin-fixed tissues requires boiling tissue sections in 1 mM EDTA buffer, pH 7.5-8.5, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-80 °C
    Stockage commentaire
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Date de péremption
    24 months
  • Antigène
    BAX (BCL2-Associated X Protein (BAX))
    Autre désignation
    BAX (BAX Produits)
    Synonymes
    anticorps BAX-ALPHA, anticorps bax-A, anticorps xBax, anticorps xlbax, anticorps BAX, anticorps bax, anticorps fj16e01, anticorps wu:fc50b10, anticorps wu:fj16e01, anticorps BCL2L4, anticorps zgc:112983, anticorps BCL2 associated X, apoptosis regulator, anticorps BCL2-associated X protein L homeolog, anticorps BCL2-associated X protein, anticorps bcl2-associated X protein, a, anticorps bcl2-associated X protein, b, anticorps BAX, anticorps bax.L, anticorps bax, anticorps baxa, anticorps Bax, anticorps baxb
    Poids moléculaire
    21kDa
    ID gène
    581
    UniProt
    Q07812
    Pathways
    Signalisation p53, Signalisation PI3K-Akt, Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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