Smooth Muscle Actin anticorps (N-Term)
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- Antigène Voir toutes Smooth Muscle Actin (ACTA2) Anticorps
- Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))
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Épitope
- N-Term
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Reactivité
- Humain, Rat, Souris, Poulet, Boeuf (Vache), Lapin, Singe, Babouin, Cobaye, Chien, Cat, Porc, Chévre, Mouton
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Smooth Muscle Actin est non-conjugé
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Application
- Immunohistochemistry (IHC), Immunofluorescence (IF), Staining Methods (StM)
- Specificité
- Actin is a major component of the cytoskeleton and is present in most cell types. This MAb is highly specific to actin from smooth muscles. Its epitope lies in the first four N-terminal amino acids. This MAb does not stain cardiac or skeletal muscle, however, it does stain myofibroblasts and myoepithelial cells. This antibody could be used together with anti-muscle specific actin and myogenin in making a diagnosis of smooth muscle and skeletal muscle tumors. In most cases of rhabdomyosarcoma, this antibody yields negative results whereas anti-muscle specific actin and myogenin are positive. Leiomyosarcomas are positive only with anti-muscle specific actin and anti-smooth muscle actin and are negative with anti-myogenin.
- Purification
- Purified by Protein A/G
- Immunogène
- N-Terminal decapeptide of alpha smooth muscle isoform of actin and conjugated to KLH.
- Clone
- SPM332
- Isotype
- IgG2a kappa
- Top Product
- Discover our top product ACTA2 Anticorps primaire
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- Indications d'application
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Positive Control: Blood vessels in all tissues, smooth muscle or leiomyosarcoma.
Known Application: Immunofluorescence (0.5-1 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- Restrictions
- For Research Use only
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- Concentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-80 °C
- Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Date de péremption
- 24 months
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- Antigène
- Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))
- Autre désignation
- ACTA2 (ACTA2 Produits)
- Synonymes
- anticorps AAT6, anticorps ACTSA, anticorps MYMY5, anticorps GAMMA-ACTIN, anticorps ACT, anticorps ACTA3, anticorps ACTE, anticorps ACTL3, anticorps ACTSG, anticorps Act-4, anticorps Act4, anticorps SMGA, anticorps 0610041G09Rik, anticorps Actvs, anticorps SMalphaA, anticorps a-SMA, anticorps alphaSMA, anticorps wu:fb63d03, anticorps ASMA, anticorps SMactin, anticorps a-sma, anticorps aat6, anticorps actsa, anticorps mymy5, anticorps sm-actin, anticorps ACTA2, anticorps actc1, anticorps ACT-4, anticorps asma, anticorps ACTGE, anticorps actin, alpha 2, smooth muscle, aorta, anticorps actin, gamma 2, smooth muscle, enteric, anticorps actin, alpha 2, smooth muscle, aorta L homeolog, anticorps ACTA2, anticorps ACTG2, anticorps Actg2, anticorps Acta2, anticorps acta2, anticorps acta2.L
- Poids moléculaire
- 42kDa
- ID gène
- 59
- UniProt
- P62736
- Pathways
- Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development
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